次优剂量的重组人促红细胞生成素可显著降低血清铁蛋白水平。
Sub-optimal doses of human recombinant erythropoietin markedly lower serum ferritin.
作者信息
Jones-Lecointe A, Green P J, Lee H A
机构信息
Haematology Department, St. Mary's Hospital, Portsmouth, Hants, UK.
出版信息
Clin Lab Haematol. 1991;13(3):251-3. doi: 10.1111/j.1365-2257.1991.tb00280.x.
Abstract
Human recombinant erythropoietin in full dose substantially raises the haemoglobin in patients with end stage renal disease on dialysis. In lower doses no or little rise in haemoglobin is achieved but the ferritin, often very high before treatment, is disproportionately lowered. The hormone therefore may be useful in reducing iron overload in other situations.
摘要
全剂量的重组人促红细胞生成素能显著提高接受透析的终末期肾病患者的血红蛋白水平。较低剂量时，血红蛋白没有升高或仅有少量升高，但铁蛋白（治疗前通常很高）却不成比例地降低。因此，这种激素在其他情况下可能有助于减轻铁过载。
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