肺炎链球菌台湾19F-14克隆株在希腊儿童中的传播。
Spread of the Streptococcus pneumoniae Taiwan19F-14 clone among children in Greece.
作者信息
Mavroidi A, Paraskakis I, Pangalis A, Kirikou E, Charisiadou A, Athanasiou T, Tassios P T, Tzouvelekis L S
机构信息
Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, London, UK.
出版信息
Clin Microbiol Infect. 2007 Dec;13(12):1213-6. doi: 10.1111/j.1469-0691.2007.01837.x. Epub 2007 Oct 18.
Serotype 19F pneumococci were a leading cause of infections among children in Athens, Greece during 2001-2006. In total, 143 19F isolates were typed by pulsed-field gel electrophoresis (PFGE), and 38 isolates representing the main PFGE types were also characterised by multilocus sequence typing. A diversity of distinct strains belonging to sequence types 236, 1035, 274, 172 and 319 were identified, but multidrug-resistant isolates related to the Taiwan(19F)-14 clone (ST236) constituted 76.9% of the isolates. Spread of the Taiwan(19F)-14 clone explains, in part, the high incidence of antibiotic resistance observed among pneumococci reported recently from Athens.
2001年至2006年期间，19F血清型肺炎球菌是希腊雅典儿童感染的主要原因。总共对143株19F分离株进行了脉冲场凝胶电泳（PFGE）分型，并且对代表主要PFGE类型的38株分离株也进行了多位点序列分型。鉴定出了属于序列类型236、1035、274、172和319的多种不同菌株，但与台湾（19F）-14克隆（ST236）相关的多重耐药分离株占分离株的76.9%。台湾（19F）-14克隆的传播部分解释了最近雅典报告的肺炎球菌中观察到的抗生素耐药性高发生率。
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