Braga Luis H P, Lorenzo Armando J, Skeldon Sean, Dave Sumit, Bagli Darius J, Khoury Antoine E, Pippi Salle Joao L, Farhat Walid A
Division of Urology, Hospital for Sick Children, Toronto, Ontario, Canada.
J Urol. 2007 Dec;178(6):2571-5; discussion 2575. doi: 10.1016/j.juro.2007.08.050. Epub 2007 Oct 22.
We compared retrograde endopyelotomy to redo pyeloplasty for the treatment of failed pyeloplasty in children.
Of 32 patients with recurrent ureteropelvic junction obstruction retrograde endopyelotomy was performed in 18 and redo pyeloplasty was performed in 14. Patient age, gender, side, stent placement at initial pyeloplasty, presentation of secondary ureteropelvic junction obstruction, hospital stay, complications and success rates were compared. Success was defined as radiographic relief of obstruction as determined by ultrasound or diuretic renography at latest followup.
Median patient age was 6 years (range 2 to 14) at retrograde endopyelotomy and 7.2 years (1 to 17) at redo pyeloplasty. Retrograde endopyelotomy technique consisted of holmium laser in 10 patients and cautery/balloon dilation in 8. Redo pyeloplasty was performed through a flank incision in 12 patients and by laparoscopy in 2. Retrograde endopyelotomy was successful in 39% of the patients, while redo pyeloplasty had a 100% success rate (p = 0.002). Of the patients with failed retrograde endopyelotomy 5 had a stricture greater than 1 cm and 7 were younger than 4 years. Mean length of the narrowed ureteral segment was 10.1 mm in the failed retrograde endopyelotomy group vs 5.8 mm in the successful group (p <0.01). Only 1 of 8 children (13%) had a successful retrograde endopyelotomy using cautery followed by balloon dilation. Hospital stay was 1.3 days for the retrograde endopyelotomy group and 2.9 days for the redo pyeloplasty group (p <0.01). Mean followup was 47 months (range 15 to 132) after retrograde endopyelotomy and 33.1 months (12 to 78) after redo pyeloplasty.
Retrograde endopyelotomy had a significantly lower success rate than redo pyeloplasty for correction of recurrent ureteropelvic junction obstruction after failed pyeloplasty in children. Patient age less than 4 years and narrowed ureteral segment greater than 10 mm were associated with a poor outcome after retrograde endopyelotomy.
我们比较了逆行肾盂内切开术与再次肾盂成形术治疗儿童肾盂成形术失败的疗效。
32例复发性输尿管肾盂连接部梗阻患者中,18例行逆行肾盂内切开术,14例行再次肾盂成形术。比较患者的年龄、性别、患侧、初次肾盂成形术时是否放置支架、继发性输尿管肾盂连接部梗阻的表现、住院时间、并发症及成功率。成功定义为在最近一次随访时通过超声或利尿肾图检查显示梗阻在影像学上得到缓解。
逆行肾盂内切开术患者的中位年龄为6岁(范围2至14岁),再次肾盂成形术患者为7.2岁(1至17岁)。逆行肾盂内切开术技术中,10例使用钬激光,8例使用电灼/球囊扩张。12例再次肾盂成形术通过侧腹切口进行,2例通过腹腔镜进行。逆行肾盂内切开术的成功率为39%,而再次肾盂成形术的成功率为100%(p = 0.002)。逆行肾盂内切开术失败的患者中,5例狭窄长度大于1 cm,7例年龄小于4岁。逆行肾盂内切开术失败组狭窄输尿管段的平均长度为10.1 mm,成功组为5.8 mm(p <0.01)。8例儿童中仅1例(13%)采用电灼后球囊扩张的逆行肾盂内切开术获得成功。逆行肾盂内切开术组的住院时间为1.3天,再次肾盂成形术组为2.9天(p <0.01)。逆行肾盂内切开术后的平均随访时间为47个月(范围15至132个月),再次肾盂成形术后为33.1个月(12至78个月)。
对于儿童肾盂成形术失败后复发性输尿管肾盂连接部梗阻的矫正,逆行肾盂内切开术的成功率显著低于再次肾盂成形术。年龄小于4岁和狭窄输尿管段大于10 mm与逆行肾盂内切开术后预后不良相关。