Lu Zhenwei, Mukkamala Ramakrishna
Dept. of Electrical & Computer Engineering, Michigan State University, East Lansing, MI 48824, USA.
Conf Proc IEEE Eng Med Biol Soc. 2006;2006:214-7. doi: 10.1109/IEMBS.2006.260488.
We introduce a novel technique for continuous (i.e., automatic) monitoring of cardiac output (CO) and left atrial pressure (LAP) by mathematical analysis of a pulmonary artery pressure (PAP) waveform. To obtain an initial evaluation of the technique, we applied it to PAP waveforms obtained from nine critically ill patients and compared the resulting CO and LAP estimates with standard operator-dependent thermodilution and pulmonary capillary wedge pressure measurements, respectively. We report that the technique achieved an overall CO error of 17.2% and an overall LAP error of 15.8%. With further testing, the technique may ultimately be employed so as to permit, for the first time, continuous CO and LAP monitoring in critically ill patients.
我们介绍了一种通过对肺动脉压(PAP)波形进行数学分析来连续(即自动)监测心输出量(CO)和左心房压(LAP)的新技术。为了对该技术进行初步评估,我们将其应用于9例危重症患者的PAP波形,并分别将所得的CO和LAP估计值与标准的依赖操作者的热稀释法及肺毛细血管楔压测量值进行比较。我们报告该技术的总体CO误差为17.2%,总体LAP误差为15.8%。经过进一步测试,该技术最终可能会被采用,从而首次实现对危重症患者的CO和LAP进行连续监测。