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硬性透气性角膜接触镜对圆锥角膜眼高阶像差及视觉功能的影响

Effect of higher-order aberrations on visual function in keratoconic eyes with a rigid gas permeable contact lens.

作者信息

Negishi Kazuno, Kumanomido Takashi, Utsumi Yoshikazu, Tsubota Kazuo

机构信息

Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.

出版信息

Am J Ophthalmol. 2007 Dec;144(6):924-929. doi: 10.1016/j.ajo.2007.08.004. Epub 2007 Oct 18.

Abstract

PURPOSE

To study the effect of higher-order aberrations (HOAs) on visual function in keratoconus with a rigid gas permeable (RGP) contact lens (CLs).

DESIGN

Retrospective nonrandomized study.

METHODS

Thirteen eyes of 10 subjects with keratoconus who wore a RGP CLs (KC-RGP group), 15 eyes of nine normal subjects (normal group), and 14 eyes of nine subjects who wore a RGP CLs (RGP group) who had no ocular diseases except for refractive errors and had 20/20 or better-corrected visual acuity were included in this study. The root-mean-square (RMS) of the third-, fourth-, fifth-, and sixth-order Zernike coefficients (total HOAs), the RMS of the third-order Zernike coefficients (S3) (coma-like aberration), the RMS of the fourth-order coefficients (S4) (spherical-like aberrations), and the area under the log contrast sensitivity function (AULCSF) were evaluated.

RESULTS

The AULCSF in the KC-RGP group was significantly lower than in the other two groups. The total HOAs, S3, and S4 in the KC-RGP group were significantly higher than in the other two groups. There were significant negative correlations between the area under the log contrast sensitivity function and the total HOAs, S3, and S4.

CONCLUSIONS

The visual performance in a keratoconic eye with a RGP CLs degrades compared with normal eyes with and without RGP CLs, even if the corrected VA is good. The degradation is assumed to be related to residual HOAs in a keratoconic eye with a RGP CLs.

摘要

目的

研究硬性透气性(RGP)隐形眼镜(CLs)对圆锥角膜高阶像差(HOAs)视觉功能的影响。

设计

回顾性非随机研究。

方法

本研究纳入10例佩戴RGP CLs的圆锥角膜患者的13只眼(圆锥角膜-RGP组)、9例正常受试者的15只眼(正常组)以及9例除屈光不正外无眼部疾病且矫正视力为20/20或更好的佩戴RGP CLs的受试者的14只眼(RGP组)。评估了三阶、四阶、五阶和六阶泽尼克系数的均方根(RMS)(总高阶像差)、三阶泽尼克系数的RMS(S3)(类彗差像差)、四阶系数的RMS(S4)(类球差像差)以及对数对比敏感度函数下的面积(AULCSF)。

结果

圆锥角膜-RGP组的AULCSF显著低于其他两组。圆锥角膜-RGP组的总高阶像差、S3和S4显著高于其他两组。对数对比敏感度函数下的面积与总高阶像差、S3和S4之间存在显著负相关。

结论

即使矫正视力良好,佩戴RGP CLs的圆锥角膜眼的视觉性能与佩戴和未佩戴RGP CLs的正常眼相比仍会下降。这种下降被认为与佩戴RGP CLs的圆锥角膜眼中残留的高阶像差有关。

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