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穿透性角膜移植术后硬性透气性角膜接触镜的对比视力研究。

Investigation of contrast visual acuity with rigid gas permeable contact lenses after penetrating Keratoplasty.

机构信息

Shandong First Medical University & Shandong Academy of Medical Sciences, Shandong, Jinan, China.

Medical School of Ophthalmology and optometry, Shandong University of Traditional Chinese medicine, Jinan, Shandong, China.

出版信息

BMC Ophthalmol. 2023 Jan 9;23(1):12. doi: 10.1186/s12886-023-02769-9.

Abstract

BACKGROUND

To investigate the effects of rigid gas permeable contact lens (RGP-CL) wear on contrast visual acuity in patients after penetrating keratoplasty.

METHODS

Nineteen patients (19 eyes), aged 30.45 ± 5.83 years, who had received penetrating keratoplasty and were successfully fitted with RGP-CLs at our hospital from July 2017 to June 2018 were included. Contrast visual acuities at 100%, 25%, and 10% with spectacles and RGP-CLs were analyzed using the Chi-square test. The wavefront aberrations at the anterior surface of the cornea before and 1 month after RGP-CL wear were compared using the matched sample t-test.

RESULTS

The mean best spectacle-corrected visual acuities were 0.390 ± 0.135 logMAR, 0.706 ± 0.182 logMAR, and 0.952 ± 0.223 logMAR at the 100%, 25%, and 10% contrast levels, respectively, which were significantly lower than the RGP-CL-corrected visions at the three levels (0.255 ± 0.133 logMAR, 0.488 ± 0.168 logMAR, and 0.737 ± 0.159 logMAR; all P < 0.001). The vision losses with RGP-CLs were 0.231 ± 0.099 logMAR and 0.466 ± 0.094 logMAR at the 25% and 10% contrast levels, respectively. The Zernike spherical aberration Z was reduced from 3.734 ± 1.061 μm to 2.622 ± 0.725 μm after wearing the RGP-CLs (P ≤ 0.001). The astigmatism parameters of Z and Z were also reduced from 3.761 ± 2.309 μm and 3.316 ± 2.147 μm to 2.637 ± 1.722 μm and 2.016 ± 1.184 μm, respectively (P < 0.05).

CONCLUSION

For post-keratoplasty patients, RGP-CLs can help to improve visual performance, especially low contrast visual acuity. The improvement may be related to the reduction of corneal aberrations, mainly the spherical and astigmatism aberrations.

摘要

背景

研究硬性透气性角膜接触镜(RGP-CL)对穿透性角膜移植术后患者对比敏感度视力的影响。

方法

纳入 2017 年 7 月至 2018 年 6 月在我院成功接受穿透性角膜移植术并佩戴 RGP-CL 的 19 例(19 眼)患者,年龄 30.45±5.83 岁。使用卡方检验分析戴眼镜和 RGP-CL 时 100%、25%和 10%对比度的对比敏感度视力。采用配对样本 t 检验比较佩戴 RGP-CL 前后角膜前表面的波前像差。

结果

最佳矫正视力分别为戴眼镜时的 0.390±0.135 logMAR、0.706±0.182 logMAR 和 0.952±0.223 logMAR,低于佩戴 RGP-CL 时的视力(分别为 0.255±0.133 logMAR、0.488±0.168 logMAR 和 0.737±0.159 logMAR;均 P<0.001)。25%和 10%对比度时,RGP-CL 引起的视力损失分别为 0.231±0.099 logMAR 和 0.466±0.094 logMAR。佩戴 RGP-CL 后,Zernike 球差 Z 从 3.734±1.061 μm 降低至 2.622±0.725 μm(P≤0.001)。Z 和 Z 的散光参数也从 3.761±2.309 μm 和 3.316±2.147 μm 降低至 2.637±1.722 μm 和 2.016±1.184 μm(P<0.05)。

结论

对于角膜移植术后患者,RGP-CL 可以帮助改善视力,特别是低对比度视力。这种改善可能与角膜像差的减少有关,主要是球差和散光像差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/571e/9830785/9dafee56e943/12886_2023_2769_Fig1_HTML.jpg

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