Açil Tayfun, Cölkesen Yücel, Türköz Riza, Sezgin Alpay Turan, Baltali Mehmet, Gülcan Oner, Demircan Senol, Yildirir Aylin, Ozin Bülent, Müderrisoğlu Haldun
Department of Cardiology, Başkent University, Ankara, Turkey.
Am J Cardiol. 2007 Nov 1;100(9):1383-6. doi: 10.1016/j.amjcard.2007.06.025. Epub 2007 Aug 16.
The value of echocardiography, especially tissue Doppler imaging (TDI), in the assessment of risk of postoperative atrial fibrillation (AF) after coronary artery bypass grafting (CABG) is not clear. One hundred two consecutive patients (80 men; mean age 61 +/- 10 years) who underwent elective isolated CABG were included in the study. All patients underwent conventional transthoracic echocardiography and TDI of the left and right heart before surgery. Also, 24-hour Holter recordings were obtained for all patients. The study end point was the development of postoperative AF. The surgical mortality rate was 2%. Postoperative AF occurred in 18 patients (18%). Patients with postoperative AF have been significantly older than patients without postoperative AF (73 +/- 7 vs 58 +/- 9 years, respectively; p <0.001). Compared with patients without postoperative AF, a significantly higher proportion of patients with postoperative AF experienced paroxysmal AF before surgery (6% vs 33%, respectively; p = 0.001). Patients with postoperative AF had a significantly larger mean left atrial diameter compared with patients without postoperative AF (37 +/- 3 vs 35 +/- 3 mm, respectively; p = 0.012). Multivariate logistic regression analysis identified age as the most significant predictor of postoperative AF (odds ratio 1.254, 95% confidence interval 1.127 to 1.396; p <0.001). Of the echocardiographic variables, only left atrial diameter was identified as a significant predictor of postoperative AF (odds ratio 1.250, 95% confidence interval 1.055 to 1.562; p = 0.047). In conclusion, in the prediction of postoperative AF after isolated CABG, preoperative transthoracic echocardiography, including both conventional echocardiography and TDI, is of little value.
超声心动图,尤其是组织多普勒成像(TDI),在评估冠状动脉旁路移植术(CABG)后发生术后房颤(AF)的风险方面价值尚不明确。本研究纳入了102例连续接受择期单纯CABG的患者(80例男性;平均年龄61±10岁)。所有患者在手术前均接受了常规经胸超声心动图检查以及左右心的TDI检查。此外,所有患者均进行了24小时动态心电图记录。研究终点为术后房颤的发生。手术死亡率为2%。18例患者(18%)发生了术后房颤。发生术后房颤的患者比未发生术后房颤的患者年龄显著更大(分别为73±7岁和58±9岁;p<0.001)。与未发生术后房颤的患者相比,发生术后房颤的患者术前发生阵发性房颤的比例显著更高(分别为6%和33%;p=0.001)。与未发生术后房颤的患者相比,发生术后房颤的患者平均左心房直径显著更大(分别为37±3mm和35±3mm;p=0.012)。多因素逻辑回归分析确定年龄是术后房颤最显著的预测因素(比值比1.254,95%置信区间1.127至1.396;p<0.001)。在超声心动图变量中,只有左心房直径被确定为术后房颤的显著预测因素(比值比1.250,95%置信区间1.055至1.562;p=0.047)。总之,在预测单纯CABG术后的房颤方面,术前经胸超声心动图检查,包括常规超声心动图和TDI,价值不大。