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伊维菌素和左旋咪唑对沙特阿拉伯阿拉伯沙瞪羚(Gazella subgutturosa marica)和阿拉伯山瞪羚(Gazella gazella)自然感染斯氏细颈线虫的疗效。

The efficacy of ivermectin and levamisole against natural Nematodirus spathiger infection in the Arabian sand gazelle (Gazella subgutturosa marica) and the Arabian mountain gazelle (Gazella gazella) in Saudi Arabia.

作者信息

Mohammed Osama B, Omer Sawsan A, Sandouka Mohammed A

机构信息

King Khalid Wildlife Research Centre, National Commission for Wildlife Conservation and Development, P.O. Box 61681, Riyadh 1175, Saudi Arabia.

出版信息

Vet Parasitol. 2007 Nov 30;150(1-2):170-3. doi: 10.1016/j.vetpar.2007.09.009. Epub 2007 Oct 24.

Abstract

The efficacy of two broad spectrum anthelmintics (Ivermectin and Levamisole) against the nematode Nematodirus spathiger in the reem (Arabian sand gazelle) and idmi (Arabian mountain gazelle) at King Khalid Wildlife Research Centre (KKWRC) was determined. Gazelles of both species naturally infected with N. spathiger were each divided into 3 groups. One group was treated with Ivermectin, the other group with Levamisole and the last group was left as untreated control. Faecal egg counts were employed to determine the efficacy of the two drugs against N. spathiger infection in both gazelle species. Reduction in arithmetic mean faecal egg counts achieved by Ivermectin and Levamisole in the reem gazelles was 94% and 89.3%, respectively. The reduction in the idmi gazelles was 97.2% and 96.4%, respectively. Hence, both anthelmintics appeared to be more effective in the idmi gazelles than in the reem gazelles, however, there was no significant difference in the faecal egg reduction tests in both animal species.

摘要

在哈利德国王野生动物研究中心(KKWRC),测定了两种广谱驱虫药(伊维菌素和左旋咪唑)对阿拉伯沙瞪羚和阿拉伯山地瞪羚体内的斯氏细颈线虫的疗效。将两种自然感染斯氏细颈线虫的瞪羚各分为3组。一组用伊维菌素治疗,另一组用左旋咪唑治疗,最后一组作为未治疗的对照。采用粪便虫卵计数法来测定这两种药物对两种瞪羚体内斯氏细颈线虫感染的疗效。伊维菌素和左旋咪唑使阿拉伯沙瞪羚粪便虫卵算术平均计数的减少率分别为94%和89.3%。在阿拉伯山地瞪羚中,减少率分别为97.2%和96.4%。因此,两种驱虫药在阿拉伯山地瞪羚中似乎比在阿拉伯沙瞪羚中更有效,然而,两种动物的粪便虫卵减少试验中没有显著差异。

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