Stein C M, Svoren B, Davis P, Blankenberg B
Department of Clinical Pharmacology, University of Zimbabwe Medical School, Harare.
J Rheumatol. 1991 Dec;18(12):1841-4.
In a 10-month prospective study a research assistant identified 411 patients with rheumatic disease at the 2 referral hospitals in Harare. Rheumatic disease accounted for less than 1% of hospital admissions. Rheumatoid arthritis, the commonest condition, accounted for 18% of patients, many of whom had impaired functional capacity. Septic arthritis (16%) was common in younger patients, often affecting the hip or knee and often associated with other complications of disseminated staphylococcal infection. Osteoarthritis (9%), rheumatic fever (7%), gout (6%), human immunodeficiency virus associated musculoskeletal problems (6%) and systemic lupus erythematosus (5%) were relatively common while the spondyloarthropathies occurred less frequently. The spectrum of rheumatic disease seen in teaching hospitals in Harare, although significantly different from that seen in Europe and North America, approximates the pattern seen in developed countries more closely than previous studies from Africa would suggest.
在一项为期10个月的前瞻性研究中,一名研究助理在哈拉雷的两家转诊医院识别出411例风湿性疾病患者。风湿性疾病占医院入院人数的比例不到1%。类风湿性关节炎是最常见的病症,占患者的18%,其中许多人的功能能力受损。化脓性关节炎(16%)在年轻患者中很常见,常累及髋关节或膝关节,且常与播散性葡萄球菌感染的其他并发症相关。骨关节炎(9%)、风湿热(7%)、痛风(6%)、人类免疫缺陷病毒相关肌肉骨骼问题(6%)和系统性红斑狼疮(5%)相对常见,而脊柱关节病的发生率较低。哈拉雷教学医院中所见的风湿性疾病谱,虽然与欧洲和北美所见的有显著差异,但比非洲以往的研究表明的情况更接近发达国家所见的模式。