Rasmussen Birgitte Bruun, Bak Martin, Rank Fritz E
Nordsjaellands Hospital, Patologiafdelingen, Hillerød.
Ugeskr Laeger. 2007 Sep 3;169(36):2985-7.
The golden standard in non-operative breast cancer diagnosis is the triple test, a combination of clinical evaluation, mammography/ultrasound and needle biopsy, either fine needle aspiration cytology (FNAC) or histological core biopsy. FNAC and core biopsy both have advantages and disadvantages but neither of them can act as a decisive diagnostic procedure on its own. The final diagnosis should always be a consensus between the three diagnostic modalities in the triple test. Quality assurance of the pathological diagnosis is a must. The number of uncertain diagnoses i.e. atypia or suspicion of malignancy should be kept at a minimum. These diagnostic categories call for additional diagnostic procedures and thereby cause a delay in reaching the final diagnosis leading to definitive treatment.
非手术性乳腺癌诊断的金标准是三联检测,即临床评估、乳腺钼靶/超声检查与穿刺活检(细针穿刺抽吸活检或组织芯活检)相结合。细针穿刺抽吸活检和组织芯活检都有优缺点,但两者都不能单独作为决定性的诊断方法。最终诊断应始终是三联检测中三种诊断方式之间的共识。病理诊断的质量保证是必不可少的。不确定诊断(即非典型增生或疑似恶性肿瘤)的数量应保持在最低限度。这些诊断类别需要额外的诊断程序,从而导致最终诊断延迟,进而延误确定性治疗。