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[终末期心力衰竭的目标治疗。心脏移植的一种可能替代方案?]

[Destination therapy in end-stage heart failure. A possible alternative to heart transplantation?].

作者信息

Olsen Peter Skov, Sander Kåre, Hansen Peter Bo, Mortensen Svend Aage, Gustafsson Finn, Boesgaard Søren

机构信息

Rigshospitalet, Hjertecentret, Thoraxkirurgisk Klinisk, København

出版信息

Ugeskr Laeger. 2007 Sep 24;169(39):3287-9.

Abstract

The incidence of heart failure continues to increase but the number of available heart donors is limited. Implantation of circulatory assist devices as a permanent alternative to heart transplantation has become a promising new alternative in patients not eligible for heart transplantation (destination therapy). New technical advances have increased the durability of the devices and reduced complications.New generations of rotator pumps are smaller and more durable and will expand the use of these devices for destination therapy. This review discusses the current state of knowledge and indications for destination therapy in end-stage heart failure.

摘要

心力衰竭的发病率持续上升,但可用的心脏供体数量有限。植入循环辅助装置作为心脏移植的永久性替代方案,已成为不适于心脏移植患者(终末期治疗)的一种有前景的新选择。新技术进展提高了装置的耐用性并减少了并发症。新一代旋转泵体积更小、更耐用,将扩大这些装置在终末期治疗中的应用。本文综述了终末期心力衰竭终末期治疗的当前知识状况和适应症。

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