Helal I, Abderrahim E, Ben Hamida F, Zouaghi K, Ounissi M, Barbouche S, Hedri H, Ezzine S, Ben Abdallah I, Chrif M, Bardi R, Ayed K, Ben Maiz H, Ben Abdallah T, Kheder A
Department of Internal Medicine A , Charles Nicolle Hospital, Boulevard du 9 Avril, 1006 Tunis, Tunisia.
Transplant Proc. 2007 Oct;39(8):2547-9. doi: 10.1016/j.transproceed.2007.08.017.
Studies looking at the type of pretransplantation renal replacement therapy on graft and patient survivals after kidney transplantation have produced conflicting results. Therefore, we studied the effect of pretransplantation dialysis modality (peritoneal dialysis [PD] or hemodialysis [HD]) on transplant outcomes. We performed a retrospective study of 78 patients (39 PD and 39 HD) who had their first renal transplantation between January 1986 and December 2004. Comparisons between groups were made using chi-square tests for qualitative parameters and nonpaired Student t tests for continuous variables. Comparisons between actuarial curves of patient and technique survivals used log-rank tests. The percentages of recipient males, cadaveric donors, transplant-induced diabetes, mean period of dialysis, mean transplantation follow-up, mean duration of first hospital stay, first infection, acute tubular necrosis, and acute rejection episodes were not significantly different among PD versus HD patients, whereas recipient and donor mean ages were significantly higher in HD and PD patients, respectively. There were no differences in graft and recipient survivals among PD versus HD patients. After kidney transplantation, there was no difference between PD and HD patients concerning percentages of infection, acute tubular necrosis, acute rejection episodes or graft and recipient survivals.
关于肾移植前肾脏替代治疗类型对肾移植后移植物和患者存活率影响的研究结果相互矛盾。因此，我们研究了肾移植前透析方式（腹膜透析[PD]或血液透析[HD]）对移植结局的影响。我们对1986年1月至2004年12月期间首次进行肾移植的78例患者（39例PD和39例HD）进行了回顾性研究。使用卡方检验对定性参数进行组间比较，使用非配对学生t检验对连续变量进行组间比较。使用对数秩检验对患者和技术存活率的精算曲线进行组间比较。PD组和HD组患者中男性受者、尸体供者、移植后糖尿病、平均透析时间、平均移植随访时间、首次住院平均时长、首次感染、急性肾小管坏死和急性排斥反应发作的百分比无显著差异，而HD组患者受者和供者的平均年龄分别显著高于PD组患者。PD组和HD组患者的移植物和受者存活率无差异。肾移植后，PD组和HD组患者在感染百分比、急性肾小管坏死、急性排斥反应发作或移植物和受者存活率方面无差异。
