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麦地那龙线虫病、盘尾丝虫病、血吸虫病和沙眼。

Dracunculiasis, onchocerciasis, schistosomiasis, and trachoma.

作者信息

Hopkins Donald R, Richards Frank O, Ruiz-Tiben Ernesto, Emerson Paul, Withers P Craig

机构信息

Health Programs, The Carter Center, 453 Freedom Pkwy., Atlanta, GA 30307, USA.

出版信息

Ann N Y Acad Sci. 2008;1136:45-52. doi: 10.1196/annals.1425.015. Epub 2007 Oct 22.

Abstract

The four diseases discussed in this chapter (dracunculiasis, onchocerciasis, schistosomiasis, and trachoma) are among the officially designated "Neglected Tropical Diseases," and each is also both the result of and a contributor to the poverty of many rural populations. To various degrees, they all have adverse effects on health, agricultural productivity, and education. The Carter Center decided to work on these health problems because of their adverse effect on the lives of poor people and the opportunity to help implement effective interventions. As a result of the global campaign spearheaded by the Carter Center since 1986, the extent of dracunculiasis has been reduced from 20 to five endemic countries and the number of cases reduced by more than 99%. We have helped administer nearly 20% of the 530 million Mectizan (ivermectin) doses for onchocerciasis, which is now being controlled throughout most of Africa, and is progressing toward elimination in the Americas. Since 1999, two Nigerian states have been using village-based health workers originally recruited to work on onchocerciasis to also deliver mass treatment and health education for schistosomiasis and lymphatic filariasis. They now also distribute vitamin A supplements and bed nets to prevent malaria and lymphatic filariasis. Ethiopia aims to eliminate blinding trachoma in the Amhara Region of that highest-endemicity country by 2012, already constructing more than 300,000 latrines and other complementary interventions. Because of the synergy between these diseases and poverty, controlling or eliminating the disease also reduces poverty and increases self-reliance.

摘要

本章所讨论的四种疾病(麦地那龙线虫病、盘尾丝虫病、血吸虫病和沙眼)属于官方指定的“被忽视的热带病”,并且每一种疾病既是许多农村人口贫困的结果,也是造成贫困的因素。它们都在不同程度上对健康、农业生产力和教育产生不利影响。卡特中心决定致力于解决这些健康问题,是因为它们对贫困人口的生活产生不利影响,也因为有机会帮助实施有效的干预措施。自1986年卡特中心牵头开展全球防治运动以来,麦地那龙线虫病的流行范围已从20个流行国家减少到5个,病例数减少了99%以上。我们协助发放了用于治疗盘尾丝虫病的5.3亿剂美迪善(伊维菌素)中的近20%,目前盘尾丝虫病在非洲大部分地区得到控制,并正在美洲朝着消除的目标迈进。自1999年以来,尼日利亚的两个州一直在利用最初招募来防治盘尾丝虫病的村级卫生工作者,为血吸虫病和淋巴丝虫病提供群体治疗和健康教育。他们现在还分发维生素A补充剂和蚊帐,以预防疟疾和淋巴丝虫病。埃塞俄比亚的目标是到2012年在该国高度流行的阿姆哈拉地区消除致盲性沙眼,目前已经建造了30多万个厕所及采取了其他辅助干预措施。由于这些疾病与贫困之间存在协同关系,控制或消除这些疾病也能减少贫困并增强自力更生能力。

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