Rosenkranz H S, Takihi N, Klopman G
Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, PA 15261.
Mutagenesis. 1991 Sep;6(5):391-4. doi: 10.1093/mutage/6.5.391.
Starting with the results of the mutagenicity of 100 chemicals, we use CASE, a structure activity relational system, to select additional chemicals for inclusion into a data base. We demonstrate that a data base consisting of approximately 180 carefully selected chemicals is as predictive as the analysis based upon 820 'unselected' chemicals.
