Karaye K M, Nashabaru I, Fika G M, Ibrahim D A, Maiyaki B M, Ishaq N A, Abubakar L Y, Nalado A M, Hassan M, Bello A K, Yusuf S M
Department of Medicine, Bayero University/Aminu Kano Teaching Hospital, Kano, Nigeria.
Cardiovasc J Afr. 2007 Sep-Oct;18(5):290-4. Epub 2007 Oct 22.
Stroke is an important cause of morbidity and mortality worldwide. The case fatality rates from stroke are two- to three-fold higher in sub-Saharan Africa, including Nigeria, than in the developed world, mainly because of limited healthcare facilities and untreated risk factors. The aim was to determine the prevalence of traditional cardiovascular risk factors among Nigerians with stroke and compare the prevalence of risk factors between young and older adults with stroke.
The study was cross-sectional in design, and was carried out on stroke patients who were 15 years of age or older, in the medical wards and neurology clinic of Aminu Kano Teaching Hospital, Nigeria. Data was collated consecutively over six months.
A total of 81 patients were studied. Sixteen of them (19.8%) were under 45 years old (group 1) while the remaining 65 patients (80.2%) were 45 years or older (group 2). All patients had at least one risk factor. One-third of group 1 patients (37.5%) and 81.5% of group 2 patients had three or more cardiovascular risk factors (p = 0.0004). The most widespread risk factor in all patients, particularly in group 2 patients was systemic hypertension, while dyslipidaemia was most common among group 1 patients. Recurrent stroke was significantly more common among group 2 than group 1 patients (30.8 and 6.3% respectively) (p = 0.045).
Cardiovascular risk factors, particularly hypertension and dyslipidaemia were prevalent in the studied patients with stroke. The older patients in group 2 had more multiple-risk factors than the younger ones in group 1. Secondary prevention strategies including detection and treatment of risk factors may curtail the burden of the disease.
中风是全球发病和死亡的重要原因。撒哈拉以南非洲地区(包括尼日利亚)的中风病死率比发达国家高出两到三倍,主要原因是医疗设施有限以及危险因素未得到治疗。本研究旨在确定尼日利亚中风患者中传统心血管危险因素的患病率,并比较年轻和老年中风患者之间危险因素的患病率。
本研究采用横断面设计,对尼日利亚阿明努·卡诺教学医院内科病房和神经科诊所15岁及以上的中风患者进行研究。连续六个月收集数据。
共研究了81例患者。其中16例(19.8%)年龄在45岁以下(第1组),其余65例患者(80.2%)年龄在45岁及以上(第2组)。所有患者至少有一个危险因素。第1组三分之一的患者(37.5%)和第2组81.5%的患者有三个或更多心血管危险因素(p = 0.0004)。所有患者中最普遍的危险因素,尤其是第2组患者,是系统性高血压,而血脂异常在第1组患者中最为常见。第2组患者复发性中风明显比第1组患者更常见(分别为30.8%和6.3%)(p = 0.045)。
心血管危险因素,尤其是高血压和血脂异常,在所研究的中风患者中普遍存在。第2组老年患者比第1组年轻患者有更多的多重危险因素。包括危险因素检测和治疗在内的二级预防策略可能会减轻疾病负担。