Doan Nhuan Ngoc, Le Thach Ngoc, Nguyen Hao Cong, Hansen Poul Erik, Duus Fritz
Department of Science, Systems and Models, Roskilde University, P. O. Box 260, DK-4000 Roskilde, Denmark.
Molecules. 2007 Aug 28;12(8):2080-8. doi: 10.3390/12082080.
Racemic 5,9-dimethylpentadecane and 5,9-dimethylhexadecane, the major and minor constituents, respectively, of the sex pheromone of Leucoptera coffeella, have been synthesized from citronellol in 56-58% overall yield through six steps. Ultrasound irradiation efficiently supported tosylation of alcohols (two steps) as well as the subsequent cross coupling reactions with the pertinent Grignard reagents (also two steps).
消旋5,9 - 二甲基十五烷和5,9 - 二甲基十六烷分别是咖啡潜叶蛾性信息素的主要成分和次要成分，已以香茅醇为原料，通过六步反应以56 - 58%的总收率合成。超声辐射有效地促进了醇的甲苯磺酰化反应（两步）以及随后与相关格氏试剂的交叉偶联反应（也是两步）。
