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隐性脊髓栓系综合征终丝切断术:寻求科学答案

Section of the terminal filum for occult tethered cord syndrome: toward a scientific answer.

作者信息

Steinbok Paul, MacNeily Andrew E

机构信息

Division of Neurosurgery, Department of Pediatric Surgery, British Columbia's Children's Hospital, Children's and Women's Health Centre, Provincial Health Services Agency, Vancouver, Canada.

出版信息

Neurosurg Focus. 2007;23(2):E5. doi: 10.3171/FOC-07/08/E5.

Abstract

The concept of an occult tethered cord syndrome (OTCS), in which a normally located conus is tethered by the terminal filum, is controversial. Children with OTCS typically present with neurogenic urinary incontinence that has been refractory to medical management. Authors of a number of case series have suggested that section of the terminal filum may improve urinary symptoms, but the quality of the evidence supporting this treatment is not good. The literature related to OTCS is reviewed and the progress toward a randomized controlled trial to assess the value of filum section in OTCS is detailed. A scientific answer to the question of filum section for OTCS awaits the results of an ongoing pilot randomized controlled trial and a more definitive trial to follow.

摘要

隐匿性脊髓拴系综合征(OTCS)的概念存在争议,该综合征中正常位置的圆锥被终丝拴系。患有OTCS的儿童通常表现为药物治疗难以治愈的神经源性尿失禁。一些病例系列的作者认为切断终丝可能改善泌尿症状,但支持这种治疗方法的证据质量不佳。本文回顾了与OTCS相关的文献,并详细阐述了评估OTCS中终丝切断价值的随机对照试验进展。关于OTCS终丝切断问题的科学答案有待正在进行的试点随机对照试验结果以及后续更具决定性的试验结果。

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