Garaffa Giulio, Bettocchi Carlo, Christopher Nim, Ralph David
St Peter's Department of Andrology, University College London Hospitals, London, UK.
J Sex Med. 2008 Jan;5(1):234-6. doi: 10.1111/j.1743-6109.2007.00629.x. Epub 2007 Oct 24.
Solitary involvement of the genitourinary tract by Von Recklinghousen disease (VRD) is extremely rare.
This report documents the management of a case of a plexiform neurofibroma on the penile shaft associated with erectile dysfunction. The literature surrounding VRD and its effects on the genital area was also investigated. Methods. After a complete preoperative investigation of the nature of the mass and of the erectile dysfunction, the neurofibroma was completely excised with preservation of the neurovascular bundle.
At 6-months postoperative follow-up, there was no sign of tumor recurrence and the glans sensation was maintained. The erectile dysfunction persisted postoperatively and failed to respond to medical treatment.
A complete excision of penile neurofibromas is mandatory to prevent recurrence or malignant degeneration and can be safely performed preserving the neurovascular bundle.
冯雷克林霍增氏病（VRD）单独累及泌尿生殖道极为罕见。
本报告记录了一例阴茎海绵体丛状神经纤维瘤伴勃起功能障碍的治疗情况。同时还对围绕VRD及其对生殖器区域影响的文献进行了研究。方法。在对肿块性质和勃起功能障碍进行全面的术前检查后，完整切除神经纤维瘤并保留神经血管束。
术后6个月随访时，无肿瘤复发迹象，龟头感觉得以保留。勃起功能障碍术后持续存在，药物治疗无效。
必须完整切除阴茎神经纤维瘤以防止复发或恶变，并且在保留神经血管束的情况下可安全进行手术。
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