Yu Meihong, Li Kaixuan, Liu Deliang, Tan Yuyong
Department of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
Research Center of Digestive Disease, Central South University, Changsha, Hunan, People's Republic of China.
Int J Gen Med. 2022 Jan 6;15:279-289. doi: 10.2147/IJGM.S339564. eCollection 2022.
The studies on solitary gastric neurofibroma (GN) consist of only individual case reports, with little data and relevant information. We aimed to summarize the clinical features, endoscopic features, imaging findings, and pathological features and study the safety and efficacy of endoscopic treatment of solitary GN.
We retrospectively collected and analyzed clinical data of patients who underwent endoscopic treatment in Department of Gastroenterology of a well-known tertiary hospital from August 2007 to September 2019 and were accurately diagnosed as having solitary GN.
A total of 788 patients with gastric submucosal tumors underwent endoscopic treatment, among whom 11 patients were found to have solitary GNs. The incidence of solitary GNs was 1.4%. All 11 patients were treated with endoscopy. Five patients underwent endoscopic full-thickness resection (EFTR) and six patients underwent endoscopic submucosal excavation (ESE). The en bloc resection rate of the 11 lesions was 100.0%. The median endoscopic operation time was 80 minutes. Average length of hospital stay was 6.4 ± 1.6 days. The median follow-up time was 29 months. No recurrence, distant metastasis, or disease-related death occurred during the follow-up.
EFTR and ESE can serve as feasible, safe, and effective treatments for solitary GN.
关于孤立性胃神经纤维瘤（GN）的研究仅包含个别病例报告，数据和相关信息较少。我们旨在总结孤立性GN的临床特征、内镜特征、影像学表现和病理特征，并研究内镜治疗孤立性GN的安全性和有效性。
我们回顾性收集并分析了2007年8月至2019年9月在某知名三级医院消化内科接受内镜治疗且被准确诊断为孤立性GN的患者的临床资料。
共有788例胃黏膜下肿瘤患者接受了内镜治疗，其中11例被发现患有孤立性GN。孤立性GN的发病率为1.4%。所有11例患者均接受了内镜治疗。5例患者接受了内镜全层切除术（EFTR），6例患者接受了内镜黏膜下挖除术（ESE）。11个病变的整块切除率为100.0%。内镜手术中位时间为80分钟。平均住院时间为6.4±1.6天。中位随访时间为29个月。随访期间未发生复发、远处转移或与疾病相关的死亡。
EFTR和ESE可作为治疗孤立性GN的可行、安全且有效的方法。
