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成功手术治疗一名患有非创伤性急性硬膜下血肿的血友病婴儿。

Successful surgical treatment of a hemophiliac infant with nontraumatic acute subdural hematoma.

作者信息

Balak Naci, Silav Gōkalp, Kiliç Yilmaz, Timur Cetin, Elmaci Ilhan

机构信息

Department of Neurosurgery, Göztepe Education and Research Hospital, Istanbul, TR-34740, Turkey.

出版信息

Surg Neurol. 2007 Nov;68(5):537-40; discussion 540. doi: 10.1016/j.surneu.2006.11.053.

Abstract

BACKGROUND

The moderate hemophiliacs usually have no spontaneous bleeding, but bleed after minor or major trauma. The proper management of intracranial hemorrhage in hemophiliac children is a challenge.

CASE DESCRIPTION

An 18-month-old male infant with moderate hemophilia A was admitted with fever, vomiting, and hypersomnia. There was no history of trauma or seizure. The CT scans showed an acute subdural hematoma in the right temporoparietooccipital region with midline shift and a coincidental right cerebellar arachnoid cyst. After bolus factor VIII replacement, a right temporoparietal craniotomy was performed, and the subdural hematoma was evacuated. The postoperative CT scans demonstrated no hematoma.

CONCLUSIONS

The possibility of intracranial hemorrhage in a moderate hemophiliac infant should be considered even if the patient has no history of trauma. The surgical treatment results in a successful outcome in hemophiliac children with subdural hematomas provided that an aggressive factor replacement therapy is initiated before surgery.

摘要

背景

中度血友病患者通常无自发性出血,但在轻微或重大创伤后会出血。血友病患儿颅内出血的恰当处理是一项挑战。

病例描述

一名18个月大的中度甲型血友病男婴因发热、呕吐和嗜睡入院。无创伤或癫痫病史。CT扫描显示右侧颞顶枕区急性硬膜下血肿伴中线移位,同时合并右侧小脑蛛网膜囊肿。在给予大剂量凝血因子VIII替代治疗后,进行了右侧颞顶部开颅手术,清除了硬膜下血肿。术后CT扫描显示无血肿。

结论

即使患者无创伤史,也应考虑中度血友病婴儿发生颅内出血的可能性。对于患有硬膜下血肿的血友病患儿,只要在手术前开始积极的凝血因子替代治疗,手术治疗就能取得成功结果。

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