Sello Guido, Orsini Fulvia, Bernasconi Silvana, Di Gennaro Patrizia
Dipartimento di Chimica Organica e Industriale, Università degli Studi di Milano, via Venezian 21, 20133 Milano, Italy.
Molecules. 2006 May 12;11(5):365-9. doi: 10.3390/11050365.
Highly selective enzymatic reductions of aldehydes to the corresponding alcohols was performed using an E. coli JM109 whole cell biocatalyst. A selective enzymatic method for the reduction of aldehydes could provide an eco-compatible alternative to chemical methods. The simplicity, fairly wide scope and the very high observed chemoselectivity of this approach are its most unique features.
使用大肠杆菌JM109全细胞生物催化剂对醛进行高度选择性的酶促还原反应,生成相应的醇。一种用于还原醛的选择性酶促方法可为化学方法提供一种生态友好型替代方案。该方法的简单性、相当广泛的适用范围以及极高的化学选择性是其最独特的特征。