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[放射治疗在骨软骨肉瘤综合治疗中的作用]

[The role of radiotherapy in combined treatment of chondrosarcoma of the bone].

作者信息

Golbicić I, Sobić V, Jelić Lj, Sbutega B

出版信息

Srp Arh Celok Lek. 1991 Mar-Apr;119(3-4):99-102.

PMID:1796337
Abstract

A retrospective analysis of 32 cases of chondrosarcoma of the bone treated by radiotherapy between 1966 and 1986 is presented. In all cases the disease was histologically confirmed. With respect to the known prognostic factors this group of patients was infavourable (75% in the trunk and the head; 69.5% with high histologic grad; 87.5% of high local aggressiveness; the wean patients' age was 37.9 years). Thirteen patients were preoperatively irradiated, 8 postoperatively and 11 received radiotherapy after the biopsy. The treatment was radical (symptomatic relief only) in 9 cases. After the treatment 30 patients were on follow-up from 4-274 months (Me = 60.8m.). According to the local control 9 patients responded to therapy (30.0%). The survival rate was 26.6% and disease-free survival rate was 20.0%.

摘要

本文对1966年至1986年间接受放疗的32例骨软骨肉瘤患者进行了回顾性分析。所有病例均经组织学确诊。就已知的预后因素而言,该组患者预后不佳(75%位于躯干和头部;69.5%组织学分级高;87.5%局部侵袭性高;患者平均年龄为37.9岁)。13例患者术前接受放疗,8例术后放疗,11例活检后接受放疗。9例患者接受了根治性治疗(仅缓解症状)。治疗后,30例患者接受了4至274个月的随访(中位数=60.8个月)。根据局部控制情况,9例患者对治疗有反应(30.0%)。生存率为26.6%,无病生存率为20.0%。

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