不应停止脊髓灰质炎疫苗接种。

Vaccination against polio should not be stopped.

作者信息

Chumakov Konstantin, Ehrenfeld Ellie, Wimmer Eckard, Agol Vadim I

机构信息

Konstantin Chumakov is at the Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, Rockville, Maryland 20852, USA.

出版信息

Nat Rev Microbiol. 2007 Dec;5(12):952-8. doi: 10.1038/nrmicro1769.

DOI:10.1038/nrmicro1769

PMID:17965726

Abstract

The striking 50-year-long decline in the incidence of poliomyelitis has stalled in the past 7 years, which has led to calls for an urgent re-assessment of eradication and post-eradication campaign strategies. The current plan of eliminating the circulation of wild poliovirus so that further immunization will be unnecessary does not take into account recent scientific data and political realities that limit the likelihood that this strategy can sustain prevention of the disease. It is crucially important that high levels of population immunity are maintained against polio in the foreseeable future.

摘要

脊髓灰质炎发病率长达50年的显著下降在过去7年中停滞不前，这引发了人们对根除和根除后运动策略进行紧急重新评估的呼声。目前消除野生脊髓灰质炎病毒传播从而无需进一步免疫的计划没有考虑到近期限制该策略维持疾病预防可能性的科学数据和政治现实。在可预见的未来维持高水平的人群对脊髓灰质炎的免疫力至关重要。