[Ⅰ型人类精浆过敏]

[Human seminal plasma allergy type I].

作者信息

Winter U M, Harth W, Treudler R, Simon J C

机构信息

Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Leipzig AöR, Philipp-Rosenthal-Str. 23-25, 04103 Leipzig.

出版信息

Hautarzt. 2008 Aug;59(8):649-52. doi: 10.1007/s00105-007-1429-3.

DOI:10.1007/s00105-007-1429-3

PMID:17965839

Abstract

Human seminal plasma allergy (HSPA) is a rare allergic reaction to specific protein fractions of seminal plasma, whereof PSA seems to be a relevant allergen. Predominantly Type I-immunoreactions can occur. The main symptoms are localized and generalized urticaria and sometimes anaphylactic symptoms. The diagnosis is based on history, skin tests and on the determination of specific IgE-levels for (un)fractionated seminal plasma. Here we report a patient with recurrent episodes of generalized urticaria after unprotected sexual intercourse and positive prick-test-reaction on seminal plasma.

摘要

人类精浆过敏（HSPA）是一种对精浆中特定蛋白质成分的罕见过敏反应，其中前列腺特异性抗原（PSA）似乎是一种相关过敏原。主要可发生I型免疫反应。主要症状为局部和全身性荨麻疹，有时还会出现过敏症状。诊断基于病史、皮肤试验以及测定（未）分级精浆的特异性IgE水平。在此，我们报告一例患者，其在无保护性交后反复出现全身性荨麻疹发作，且对精浆的点刺试验反应呈阳性。