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脾动脉栓塞术用于缓解阵发性夜间血红蛋白尿患者肝移植后顽固性腹水。

Use of splenic artery embolization to relieve tense ascites following liver transplantation in a patient with paroxysmal nocturnal hemoglobinuria.

作者信息

Chang Charissa Y, Singal Ashwani K, Ganeshan Sri V, Schiano Thomas D, Lookstein Robert, Emre Sukru

机构信息

Recanati Miller Transplant Institute, Mount Sinai Hospital, Mount Sinai School of Medicine, New York, NY, USA.

出版信息

Liver Transpl. 2007 Nov;13(11):1532-7. doi: 10.1002/lt.21317.

Abstract

Recurrent venous thrombosis following liver transplantation for Budd-Chiari syndrome is common, particularly in the setting of an underlying myeloproliferative disorder. We describe a patient who developed refractory ascites due to portal vein thrombosis following liver transplantation for Budd-Chiari syndrome in the setting of paroxysmal nocturnal hemoglobinuria. Extensive portal vein thrombosis, dense abdominal adhesions, and portosystemic collaterals precluded the use of a transjugular intrahepatic portosystemic shunt or surgical portosystemic shunt to manage the patient's ascites. Splenic artery embolization to decrease portal hypertension was performed, and this resulted in complete resolution of ascites. This case demonstrates the successful use of splenic artery embolization to manage ascites due to portal vein thrombosis following liver transplantation. Splenic artery embolization may be considered as an alternative option for the management of refractory ascites due to portal hypertension in patients who are unable to undergo safe transjugular intrahepatic portosystemic shunt or surgical shunt placement.

摘要

布加综合征肝移植后复发性静脉血栓形成很常见,尤其是在存在潜在骨髓增殖性疾病的情况下。我们描述了一名因阵发性夜间血红蛋白尿并发布加综合征行肝移植后发生门静脉血栓形成而出现难治性腹水的患者。广泛的门静脉血栓形成、致密的腹部粘连和门体侧支循环使得经颈静脉肝内门体分流术或外科门体分流术无法用于治疗该患者的腹水。进行了脾动脉栓塞以降低门静脉高压,这使得腹水完全消退。该病例证明了脾动脉栓塞成功用于治疗肝移植后门静脉血栓形成所致腹水。对于无法进行安全的经颈静脉肝内门体分流术或外科分流术放置的患者,脾动脉栓塞可被视为治疗门静脉高压所致难治性腹水的一种替代选择。

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