Meléndez-Zajgla Jorge, Maldonado Vilma
Laboratorio de Biología Molecular, Subdirección de Investigación Básica, Instituto Nacional de Cancerología, Tlalpan, México, DF, México.
Gac Med Mex. 2007 Jul-Aug;143(4):353-4.
A direct, horizontal and natural transmission of neoplasic cells has only recently been accepted by the biomedical community. There are three known examples in mammals: the Tasmanian Devil Tumor Disease, the Canine Transmissible Venereal Tumor and a similar disease in Sirian Hamsters. These diseases are not anecdotic cases only, but provide support for the cancer clonal evolution hypothesis.
肿瘤细胞直接、横向且自然的传播直到最近才被生物医学界所接受。在哺乳动物中有三个已知的例子:袋獾肿瘤病、犬传染性性病肿瘤以及叙利亚仓鼠的一种类似疾病。这些疾病并非只是个别案例,而是为癌症克隆进化假说提供了支持。