Liu Rui-Fen, Yang Xiao-Na
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Sep;27(9):841-3.
To explore the effect of Penqiangyan Granule (PG) on the immunity of patients with chronic pelvic inflammatory disease (CPID) of blood stasis and Shen-deficiency syndrome (BSSDS) type.
Sixty patients were randomly assigned to two groups: the treatment group treated with PG and the control group with Penyanjing Granule, 30 cases in each group. The treatment course was 4 weeks for both groups. The clinical efficacy, plasma levels of CD4 and CD8, and the serum levels of tumor necrosis factor-alpha (TNF-alpha) and interleukin-2 (IL-2) were measured before and after treatment.
After treatment, the total effective rate in the treatment group and the control group was 96.7% and 63.3% respectively with significant difference between groups (P < 0.05); in the treatment group the plasma CD4, CD4/CD8 and serum IL-2 increased obviously, while the plasma CD8 and serum TNF-alpha decreased markedly (P < 0.05), all were significantly different with those in the control group (P < 0.05).
PG can improve the immune function and alleviate inflammation in CPID patients of BSSDS type.
探讨盆腔炎颗粒（PG）对瘀血肾虚型慢性盆腔炎（CPID）患者免疫功能的影响。
将60例患者随机分为两组：治疗组服用PG，对照组服用盆炎净颗粒，每组30例。两组疗程均为4周。治疗前后测定临床疗效、血浆CD4和CD8水平以及血清肿瘤坏死因子-α（TNF-α）和白细胞介素-2（IL-2）水平。
治疗后，治疗组和对照组的总有效率分别为96.7%和63.3%，组间差异有统计学意义（P<0.05）；治疗组血浆CD4、CD4/CD8及血清IL-2明显升高，而血浆CD8及血清TNF-α明显降低（P<0.05），与对照组比较差异均有统计学意义（P<0.05）。
PG可改善瘀血肾虚型CPID患者的免疫功能并减轻炎症。
