Lynch Irene T, Eustace Joseph A, Plant Willliam D, Cashman Kevin D, O'Keefe Majella, Lordan Sinead, Moloney Rachel
Department of Clinical Nutrition, Cork University Hospital, Cork, Ireland.
J Ren Nutr. 2007 Nov;17(6):408-15. doi: 10.1053/j.jrn.2007.05.005.
To quantify the dietary calcium and vitamin D intake in adult renal-transplant recipients attending at a large teaching hospital in Ireland for follow-up.
Outpatient renal-transplant follow-up clinic.
Fifty-nine adult renal transplant recipients (58% male) with a mean age of 46 years, a median transplant duration of 6 years, and a mean estimated glomerular filtration rate (eGFR) of 50 mL/min per 1.73 m2. Fifty-three percent were at National Kidney Foundation stage 3 chronic kidney disease, and 14% had stage 4 chronic kidney disease.
This cross-sectional, observational study used a tailored food frequency questionnaire specific for calcium and vitamin D intake in Irish adults, which was completed during a face-to-face interview with each subject.
The main outcome measure was the average daily dietary and supplemented calcium and vitamin D intake.
The median interquartile range (IQR) dietary calcium intake was 820 mg/day (range, 576-1,177 mg/day), and was similar in men and women (recommended intake > or = 1,000 mg/day in adult men and nonmenopausal adult women, > or = 1,500 mg/day in menopausal women). Five participants received calcium supplementation. Overall, 59% of men and 64% of women had total calcium intakes below the recommended amounts. The median IQR estimated dietary vitamin D intake was 5.2 microg/day (range, 2.4-6.4 microg/day) in women, and 4.6 microg/day (range, 2.2-6.6 microg/day) in men (recommended intake, > or = 10 microg/day). Six subjects received vitamin D supplementation. Total vitamin D intakes were suboptimal in 91% of men and 87% of women. Dietary calcium and vitamin D intakes significantly correlated with each other, but neither was significantly related to eGFR category, and was similarly low in both presumed menopausal women and in the initial year posttransplantation.
These findings suggest that dietary and total calcium and vitamin D intakes in adult renal-transplant patients are in many cases inadequate.
量化爱尔兰一家大型教学医院成年肾移植受者随访期间的膳食钙和维生素D摄入量。
门诊肾移植随访诊所。
59例成年肾移植受者（男性占58%），平均年龄46岁，移植中位数时间为6年，平均估计肾小球滤过率（eGFR）为每1.73平方米50毫升/分钟。53%处于美国国家肾脏基金会3期慢性肾脏病，14%处于4期慢性肾脏病。
这项横断面观察性研究使用了一份针对爱尔兰成年人钙和维生素D摄入量的定制食物频率问卷，该问卷在与每位受试者的面对面访谈中完成。
主要观察指标是每日膳食及补充的钙和维生素D平均摄入量。
膳食钙摄入量的中位数四分位间距（IQR）为820毫克/天（范围为576 - 1177毫克/天），男性和女性相似（成年男性和未绝经成年女性的推荐摄入量≥1000毫克/天，绝经后女性≥1500毫克/天）。5名参与者接受了钙补充剂。总体而言，59%的男性和64%的女性总钙摄入量低于推荐量。估计膳食维生素D摄入量的中位数IQR在女性中为5.2微克/天（范围为2.4 - 6.4微克/天），在男性中为4.6微克/天（范围为2.2 - 6.6微克/天）（推荐摄入量≥10微克/天）。6名受试者接受了维生素D补充剂。91%的男性和87%的女性总维生素D摄入量未达最佳水平。膳食钙和维生素D摄入量之间显著相关，但两者均与eGFR类别无显著关联，且在推测的绝经后女性和移植后第一年中同样较低。
这些发现表明，成年肾移植患者的膳食及总钙和维生素D摄入量在许多情况下不足。
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