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标本长度作为结肠癌充分淋巴结清扫的围手术期替代标志物:外科医生的作用

Specimen length as a perioperative surrogate marker for adequate lymphadenectomy in colon cancer: the surgeon's role.

作者信息

Neufeld David, Bugyev Nikolay, Grankin Mila, Gutman Mordechay, Klein Ehud, Bernheim Joelle, Shpitz Baruch

机构信息

Department of Surgery, Sapir Medical Center, Meir General Hospital, Kfar Sava, Israel.

出版信息

Int Surg. 2007 May-Jun;92(3):155-60.

PMID:17972471
Abstract

The objective of this study was to determine whether there is a correlation between the length of the sigmoid colon removed and the number of harvested lymph nodes (LNs). Pathology charts of 137 sigmoid resections that were done over a 5-year period were reviewed. The length of removed sigmoid specimen reported in the pathology reports was correlated with the number of LNs retrieved from the specimen. The mean and median numbers of retrieved LNs were 9 and 10, respectively. There was an increase in the number of retrieved LNs with increasing length of resected sigmoid colon. For Dukes' B patients, the average length of the resected specimen was 15.1 cm for those with < 12 LNs and 20.3 cm for those with > 12 LNs (P = 0.01). Our data suggest that the surgeon may play an important role in determining the extent of LN harvesting during large bowel resection for cancer.

摘要

本研究的目的是确定切除的乙状结肠长度与获取的淋巴结数量之间是否存在相关性。回顾了在5年期间进行的137例乙状结肠切除术的病理图表。病理报告中报告的切除乙状结肠标本的长度与从标本中获取的淋巴结数量相关。获取的淋巴结的平均数和中位数分别为9个和10个。随着切除的乙状结肠长度增加,获取的淋巴结数量也增加。对于Dukes' B期患者,淋巴结数量<12个的患者切除标本的平均长度为15.1 cm,淋巴结数量>12个的患者切除标本的平均长度为20.3 cm(P = 0.01)。我们的数据表明,在大肠癌大肠切除术中,外科医生在确定淋巴结获取范围方面可能起着重要作用。

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Specimen length as a perioperative surrogate marker for adequate lymphadenectomy in colon cancer: the surgeon's role.标本长度作为结肠癌充分淋巴结清扫的围手术期替代标志物:外科医生的作用
Int Surg. 2007 May-Jun;92(3):155-60.
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引用本文的文献

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Ann Coloproctol. 2023 Feb;39(1):77-84. doi: 10.3393/ac.2021.00444.0063. Epub 2021 Sep 16.
2
Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study.在结直肠癌病例中,为获取足够数量的淋巴结,是否需要有特定长度的结肠直肠段进行切除?一项回顾性多中心研究。
Turk J Surg. 2020 Mar 18;36(1):23-32. doi: 10.5578/turkjsurg.4550. eCollection 2020 Mar.
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Prospective multicenter registration study of colorectal cancer: significant variations in radicality and oncosurgical quality-Swiss Group for Clinical Cancer Research Protocol SAKK 40/00.
结直肠癌前瞻性多中心注册研究:根治性及肿瘤外科手术质量的显著差异——瑞士临床癌症研究组SAKK 40/00方案
Int J Colorectal Dis. 2017 Jan;32(1):57-74. doi: 10.1007/s00384-016-2667-6. Epub 2016 Oct 7.
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Predictors of lymph node count in colorectal cancer resections: data from US nationwide prospective cohort studies.结直肠癌切除术中淋巴结计数的预测因素:来自美国全国前瞻性队列研究的数据。
Arch Surg. 2012 Aug;147(8):715-23. doi: 10.1001/archsurg.2012.353.