Stojsavljević N, Drulović J
Srp Arh Celok Lek. 1994 Mar-Apr;122(3-4):120-2.
The most frequent complication of lumbar puncture is headache. It is due to lowered intracranial tension produced by a continued leakage of cerebrospinal fluid (CSF) through the dural puncture site. Epidural injection of autologous blood has been frequently reported as highly effective in the treatment of lumbar-puncture-induced headache, with success rates of 73 to 98%. To our knowledge, in Yugoslavia there has been, so far, no report, concerning the use of this techique. The aim of this study is to evaluate the treatment of postlumbar-puncture headache by epidural blood patch in our 20 patients. Here we also describe one patient with severe headache induced by lumbar puncture, in whom we documented the CSF pressure less than atmospheric. Criteria for selection into the study included: subjective evaluation of the extent of headache and accompanying symptoms, duration of symptoms more than 48 hours, and failure of headache relief with conservative measures. We injected 3-5 ml of aseptically obtained autologous blood at the site of suspected dural puncture. When evaluated an hour after treatment, all patients experienced complete relief. In only one (5%) of 20 treated patients, headache reccurred after initial relief. We have not observed any side-effects in our patients. Our results are in harmony with the published high efficiencies of autologous epidural blood patch in the treatment of postlumbar-puncture headache. We recommend the injection of 5 ml of autologous blood in the epidural space in all patients with severe lumbar-puncture-induced headache, resistant to conservative therapy, lasting more than 24-48 hours.
腰椎穿刺最常见的并发症是头痛。这是由于脑脊液(CSF)通过硬脊膜穿刺部位持续渗漏导致颅内压降低所致。硬膜外自体血注射治疗腰椎穿刺后头痛的疗效显著,成功率为73%至98%,已有诸多报道。据我们所知,南斯拉夫至今尚无关于该技术应用的报道。本研究旨在评估硬膜外自体血填充治疗20例患者腰椎穿刺后头痛的效果。在此,我们还描述了1例因腰椎穿刺诱发严重头痛的患者,其脑脊液压力低于大气压。纳入本研究的标准包括:对头痛程度及伴随症状的主观评估、症状持续时间超过48小时以及保守治疗未能缓解头痛。我们在疑似硬脊膜穿刺部位注射了3 - 5毫升无菌采集的自体血。治疗1小时后评估发现,所有患者的头痛均完全缓解。在20例接受治疗的患者中,仅有1例(5%)在初始缓解后头痛复发。我们的患者未观察到任何副作用。我们的结果与已发表的硬膜外自体血填充治疗腰椎穿刺后头痛的高效性相符。我们建议,对于所有因腰椎穿刺诱发严重头痛、保守治疗无效且症状持续超过24 - 48小时的患者,在硬膜外间隙注射5毫升自体血。