Ikeda Shuji, Okamoto Akimitsu
The Frontier Research System, RIKEN (The Institute of Physical and Chemical Research), Wako, Saitama, 351-0198, Japan.
Photochem Photobiol Sci. 2007 Nov;6(11):1197-201. doi: 10.1039/b706956a. Epub 2007 Oct 5.
Uncharged benzothiazole-based dyes were synthesized, and their fluorescence properties were examined. These fluorescent dyes showed an intense fluorescence in aqueous solution in the presence of DNA. In addition, the fluorescence intensities were pH dependent, while those of the positively charged dyes were nearly independent of pH. The pH-dependent photophysical behavior suggests that interaction of protonated dyes with DNA results in high intensities of fluorescent emission.
合成了不带电荷的苯并噻唑基染料，并对其荧光性质进行了研究。这些荧光染料在DNA存在的水溶液中显示出强烈的荧光。此外，荧光强度与pH有关，而带正电荷的染料的荧光强度几乎与pH无关。pH依赖性光物理行为表明，质子化染料与DNA的相互作用导致了高强度的荧光发射。
