Thomas Simon R, Wedge John H, Salter Robert B
Hospital for Sick Children, Toronto, Ontario, Canada.
J Bone Joint Surg Am. 2007 Nov;89(11):2341-50. doi: 10.2106/JBJS.F.00857.
A consecutive series of seventy-six patients (101 hips) underwent primary open reduction, capsulorrhaphy, and innominate osteotomy for late-presenting developmental dislocation of the hip. They were between 1.5 and five years old at the time of surgery, which was done between 1958 and 1965. The present study was designed to review the outcome of these patients into middle age.
We located and reviewed the cases of sixty patients (eighty hips), which represents a 79% rate of follow-up at forty to forty-eight years postoperatively. Nineteen patients (twenty-four hips) had undergone total hip replacement, and three (three hips) had died of unrelated causes. The remaining thirty-eight patients (fifty-three hips) were assessed by the WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) and Oxford hip score questionnaires, physical examination, and a standing anteroposterior pelvic radiograph. The radiographs were analyzed to determine the minimum joint space width and the Kellgren and Lawrence score. Accepted indices of hip dysplasia were measured.
With use of Kaplan-Meier survival analysis and with the end point defined as total hip replacement, the survival rates at thirty, forty, and forty-five years after the reduction were 99% (95% confidence interval, +/-2.4%), 86% (95% confidence interval, +/-6.9%), and 54% (95% confidence interval, +/-16.4%), respectively. The average Oxford hip score and WOMAC score for the surviving hips were 16.8 (range, 0 to 82) and 16.7 (range, 0 to 71), respectively. Of the fifty-one hips for which radiographs were available, thirty-eight demonstrated a minimum joint space width of >2.0 mm and thirteen demonstrated definite osteoarthritis on the basis of this criterion. Osteoarthritis, according to the system of Kellgren and Lawrence, was grade 0 or 1 in twenty-nine hips, grade 2 in seven hips, and grade 3 or 4 in fifteen hips. The average center-edge and acetabular angles were 40 degrees (range, 0 degrees to 61 degrees ) and 32 degrees (range, 20 degrees to 43 degrees ), respectively. With the numbers studied, no significant association was detected between outcome and the modifiable risk factors of body mass index or age at the time of surgery. Hips in patients with bilateral involvement were at significantly greater risk of failure (p = 0.02).
This method of treatment achieves a 54% rate of survival of the hip at forty-five years. Two-thirds of the surviving hips have an excellent prognosis forty to forty-eight years after the index procedure according to the Kellgren and Lawrence score.
连续76例患者(101髋)因晚期发育性髋关节脱位接受了初次切开复位、关节囊缝合及髋臼截骨术。手术时间为1958年至1965年,手术时患者年龄在1.5岁至5岁之间。本研究旨在回顾这些患者至中年时的治疗结果。
我们查找并回顾了60例患者(80髋)的病例,这代表了术后40至48年79%的随访率。19例患者(24髋)接受了全髋关节置换术,3例(3髋)因无关原因死亡。其余38例患者(53髋)通过WOMAC(西安大略和麦克马斯特大学骨关节炎指数)和牛津髋关节评分问卷、体格检查以及站立位骨盆前后位X线片进行评估。对X线片进行分析以确定最小关节间隙宽度以及Kellgren和Lawrence评分。测量了公认的髋关节发育不良指标。
采用Kaplan-Meier生存分析,将终点定义为全髋关节置换,复位后30年、40年和45年的生存率分别为99%(95%置信区间,±2.4%)、86%(95%置信区间,±6.9%)和54%(95%置信区间,±16.4%)。存活髋关节的平均牛津髋关节评分为16.8(范围0至82),平均WOMAC评分为16.7(范围0至71)。在可获得X线片的51髋中,38髋的最小关节间隙宽度>2.0 mm,13髋根据此标准显示有明确的骨关节炎。根据Kellgren和Lawrence系统,骨关节炎在29髋为0级或1级,7髋为2级,15髋为3级或4级。平均中心边缘角和髋臼角分别为40°(范围0°至61°)和32°(范围20°至43°)。就所研究的病例数量而言,未发现结局与手术时体重指数或年龄等可改变的危险因素之间存在显著关联。双侧受累患者的髋关节失败风险显著更高(p = 0.02)。
这种治疗方法在45年时髋关节生存率为54%。根据Kellgren和Lawrence评分,三分之二的存活髋关节在初次手术后40至48年预后良好。