三卤化铟催化的氯代烷与硅烯醇盐的偶联反应。
Coupling reaction of alkyl chlorides with silyl enolates catalyzed by indium trihalide.
作者信息
Nishimoto Yoshihiro, Yasuda Makoto, Baba Akio
机构信息
Department of Applied Chemistry, Center for Atomic and Molecular Technologies (CAMT), Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
出版信息
Org Lett. 2007 Nov 22;9(24):4931-4. doi: 10.1021/ol701684n. Epub 2007 Nov 2.
PMID:17975916
Abstract
Indium(III) halide catalyzed not only the coupling of alkyl chlorides with silyl enolates derived from esters, ketones, and aldehydes to give a variety of alpha-alkylated carbonyl compounds but also one-pot, three-component reactions of aldehyde enolate, alkyl chloride, and allylsilane or alkynylsilane.
摘要
卤化铟(III)不仅催化了烷基氯化物与由酯、酮和醛衍生的硅基烯醇化物的偶联反应，生成多种α-烷基化羰基化合物，还催化了醛烯醇化物、烷基氯化物与烯丙基硅烷或炔基硅烷的一锅三组分反应。
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