Santo Augusto Hasiak
Universidade de São Paulo, Faculdade de Saúde Pública, Departamento de Epidemiologia, Brasil.
Rev Panam Salud Publica. 2007 Aug;22(2):132-40. doi: 10.1590/s1020-49892007000700008.
To study mortality trends related to chickenpox, as either the underlying or associated cause-of-death (recorded in any field of the medical section of the death certificate), in São Paulo, Brazil.
Mortality data for 1985-2004 were obtained from the multiple cause-of-death database maintained by the São Paulo State Data Analysis System (SEADE). Causes-of-death were processed using the Multiple-Causes-of-Death Tabulator.
During this 20-year period, chickenpox was identified as the underlying cause-of-death in 1 037 deaths and an associated cause in 150. The mortality coefficients were higher for chickenpox as the underlying, as opposed to the associated cause, and these declined in the analyzed period; whereas a slight increase was observed in mortality due to chickenpox as an associated cause. Seventy-six percent of the deaths were of children under 10 years of age, with the highest incidence among those under 1 year. Most deaths occurred from July to January (86.8% of 1 187 deaths), with a peak in October. In the state's capital city, the mortality coefficients for chickenpox as underlying cause and as associated cause were 47% and 50% higher, respectively, than in the rest of the state. Where chickenpox was identified as the underlying cause, pneumonias and septicemias were the major associated causes; where it was the associated cause, AIDS or neoplasia were most often the underlying cause.
Although chickenpox as the underlying cause-of-death has declined, the present study indicates that certain groups are at risk of chickenpox-related mortality, namely children 1-4 years of age and individuals with AIDS or neoplasia.
研究巴西圣保罗市水痘作为根本死因或相关死因(记录在死亡证明医学部分的任何字段)的死亡率趋势。
1985 - 2004年的死亡率数据来自圣保罗州数据分析系统(SEADE)维护的多死因数据库。死因使用多死因制表器进行处理。
在这20年期间,水痘被确定为1037例死亡的根本死因和150例死亡的相关死因。水痘作为根本死因的死亡率系数高于作为相关死因的死亡率系数,且在分析期间有所下降;而作为相关死因的水痘死亡率略有上升。76%的死亡病例为10岁以下儿童,1岁以下儿童发病率最高。大多数死亡发生在7月至1月(1187例死亡中的86.8%),10月达到峰值。在该州首府城市,水痘作为根本死因和相关死因的死亡率系数分别比该州其他地区高47%和50%。当水痘被确定为根本死因时,肺炎和败血症是主要的相关死因;当水痘是相关死因时,艾滋病或肿瘤最常是根本死因。
尽管水痘作为根本死因的情况有所下降,但本研究表明,某些群体存在与水痘相关的死亡风险,即1 - 4岁儿童以及艾滋病患者或肿瘤患者。