Ozorio Gerard, McGarity Bruce, Bak Haesung, Jordan Andrew S, Lau Henry, Marshall Cathy
Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Med J Aust. 2007 Nov 5;187(9):524-6. doi: 10.5694/j.1326-5377.2007.tb01396.x.
Autoimmune hepatitis is a rare but increasingly recognised serious complication of treatment with the tumour necrosis factor-alpha (TNF-alpha) blocking agent, infliximab. This report adds to the small but growing number of articles describing this significant adverse effect. Baseline liver function should be routinely tested in all patients receiving anti-TNF-alpha agents, and periodic monitoring for the development of hepatitis is important.
自身免疫性肝炎是一种罕见但越来越被认识到的肿瘤坏死因子-α（TNF-α）阻断剂英夫利昔单抗治疗的严重并发症。本报告增加了描述这种重大不良反应的文章数量，尽管数量不多但在不断增加。所有接受抗TNF-α药物治疗的患者都应常规检测基线肝功能，定期监测肝炎的发生情况很重要。
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