Mulhall John P, Simmons Jennifer
Urology, Memorial Sloan Kettering Cancer Center & Weill Cornell Medical Center, New York, NY, USA.
BJU Int. 2007 Dec;100(6):1313-6. doi: 10.1111/j.1464-410X.2007.07266.x.
To survey patient satisfaction, using validated questionnaires, in a group of men with erectile dysfunction who had used and responded to both sildenafil citrate and intracavernosal injection (ICI) therapy.
In all, 300 patients on ICI therapy were mailed questionnaire packets containing a survey enquiring about the patients' medical history, and two sets of the International Index of Erectile Function (IIEF) and the Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS) sexual function surveys. If patients were using sildenafil alternating with ICI they were asked to complete the IIEF and EDITS questionnaires for each therapy. To identify only patients who had an adequate response to each agent, a score of >/=22 on the EF domain of the IIEF for sildenafil and ICI was required for inclusion in the final analysis.
In all, 178 packets were evaluable; 123 men (69%) responded to ICI but not sildenafil, and 11 (6%) responded only to sildenafil and not ICI, leaving 37 patients who responded to both; these patients comprised the study population. There was no difference in EF domain score of the IIEF between the treatments; EDITS scores were significantly higher for ICI therapy than for sildenafil (P < 0.001).
In patients who alternate the use of sildenafil and ICI therapy, satisfaction appears to be higher with ICI, although the erectogenic performance is similar. This suggests that patient satisfaction does not depend solely on erection performance, and that patients might benefit from various treatment options.
使用经过验证的问卷，对一组使用西地那非枸橼酸盐和海绵体内注射（ICI）疗法且有反应的勃起功能障碍男性患者进行满意度调查。
总共向300名接受ICI治疗的患者邮寄了问卷包，其中包含一份询问患者病史的调查问卷，以及两套国际勃起功能指数（IIEF）和治疗满意度勃起功能障碍量表（EDITS）性功能调查问卷。如果患者交替使用西地那非和ICI，要求他们针对每种疗法完成IIEF和EDITS问卷。为了仅识别对每种药物有充分反应的患者，最终分析纳入标准为西地那非和ICI的IIEF勃起功能（EF）领域得分≥22分。
总共178份问卷包可评估；123名男性（69%）对ICI有反应但对西地那非无反应，11名（6%）仅对西地那非有反应而对ICI无反应，剩下37名对两者均有反应的患者；这些患者构成研究人群。两种治疗方法在IIEF的EF领域得分上没有差异；ICI疗法的EDITS得分显著高于西地那非（P<0.001）。
在交替使用西地那非和ICI疗法的患者中，尽管勃起功能相似，但ICI疗法的满意度似乎更高。这表明患者满意度并非仅取决于勃起功能，患者可能从多种治疗选择中获益。
