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临床样本中伯克霍尔德菌属假鼻疽亚种的定量分析。

Quantitation of B. Pseudomallei in clinical samples.

作者信息

Wuthiekanun Vanaporn, Limmathurotsakul Direk, Wongsuvan Gumphol, Chierakul Wirongrong, Teerawattanasook Nittaya, Teparrukkul Prapit, Day Nicholas P, Peacock Sharon J

机构信息

Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

出版信息

Am J Trop Med Hyg. 2007 Nov;77(5):812-3.

PMID:17984331
Abstract

We undertook a prospective study to quantitate Burkholderia pseudomallei in blood, urine, respiratory secretions, and pus [corrected] obtained from 414 patients with melioidosis. The median was count 1.1, 1.5 x 10(4), 1.1 x 10(5), and 1.1 x 10(7) CFU/mL in these sample types, respectively. This provides important insights into the likely feasibility of future studies such as expression microarray analysis using clinical material.

摘要

我们进行了一项前瞻性研究,以对从414例类鼻疽患者获取的血液、尿液、呼吸道分泌物和脓液[校正后]中的伯克霍尔德菌进行定量分析。这些样本类型中的菌落形成单位(CFU)计数中位数分别为1.1、1.5×10⁴、1.1×10⁵和1.1×10⁷CFU/mL。这为未来研究(如使用临床材料进行表达微阵列分析)的可能可行性提供了重要见解。

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