Lohmeier K, Distelmaier F, van den Heuvel L P, Rodenburg R J T, Smeitink J, Mayatepek E, Hoehn T
Department of General Pediatrics, Heinrich-Heine-Universität, Düsseldorf, Germany.
Neuropediatrics. 2007 Jun;38(3):148-50. doi: 10.1055/s-2007-985903.
Complex I deficiency is a frequent defect of the mitochondrial electron transport chain. We report on a 3-year-old boy, who rapidly deteriorated after sudden flushing and collapse. This fatal and unusual case was characterized by widely uncontrollable arterial hypertension. It might indicate that hypertensive crisis could be a potential manifestation of mitochondrial disorders.
复合体I缺乏是线粒体电子传递链常见的缺陷。我们报告了一名3岁男孩，他在突然脸红和虚脱后病情迅速恶化。这个致命且不寻常的病例的特征是动脉高血压广泛失控。这可能表明高血压危象可能是线粒体疾病的一种潜在表现。
