Saito Shigeru
Division of Cardiology and Catheterization Laboratories, Heart Center of ShonanKamakura General Hospital, Kamakura City, Japan.
Catheter Cardiovasc Interv. 2008 Jan 1;71(1):8-19. doi: 10.1002/ccd.21316.
Retrograde approach through the collateral channels has been recently proposed and has the potential to improve the success rate of percutaneous coronary intervention (PCI) in chronic total occlusion (CTO) lesions of the coronary arteries.
The author performed retrograde approach for CTO lesions in 45 patients from January 2006 to January 2007 at different medical institutions worldwide. The details of the techniques were examined retrospectively.
The septal branch route was used in 93% of the cases. The author classified the strategies into six types after the successful crossing of a guidewire into the target artery distal to the CTO lesion through the collateral channels. Among them, "Just landmark," "Controlled antegrade and retrograde subintimal tracking," and "Proximal true lumen puncture" strategies were used most frequently (32, 27, and 30%, respectively). The retrograde guidewires could be successfully passed distal to the CTO lesion in 37 patients (82%), among them the final PCI success was achieved in 31 patients, yielding the PCI success by pure retrograde approach of 69%. The final success rate among 45 patients including 42 patients with previous failed attempts was 84% (38 patients). There were no serious complications related to the retrograde approach.
Retrograde approach with different strategies, mainly through septal arteries, can provide a high success rate with PCI, as shown in 83% of patients with previous failed attempts at traditional PCI for CTO lesions, with there being no serious complications. More experience of this technique and its refinement are required for further improvement of PCI techniques for CTO lesions.
最近有人提出通过侧支循环采用逆行路径,这有可能提高冠状动脉慢性完全闭塞(CTO)病变经皮冠状动脉介入治疗(PCI)的成功率。
作者于2006年1月至2007年1月在全球不同医疗机构对45例CTO病变患者采用了逆行路径。对技术细节进行了回顾性研究。
93%的病例采用了间隔支路径。在导丝通过侧支循环成功穿过CTO病变远端的目标动脉后,作者将策略分为六种类型。其中,“仅作标记”“可控顺行和逆行内膜下跟踪”以及“近端真腔穿刺”策略使用最为频繁(分别为32%、27%和30%)。37例患者(82%)的逆行导丝能够成功穿过CTO病变远端,其中31例患者最终PCI成功,单纯逆行路径的PCI成功率为69%。45例患者(包括42例先前尝试失败的患者)的最终成功率为84%(38例患者)。未出现与逆行路径相关的严重并发症。
采用不同策略的逆行路径,主要通过间隔动脉,可使PCI获得较高成功率,如在83%先前传统CTO病变PCI尝试失败的患者中所示,且无严重并发症。为进一步改进CTO病变的PCI技术,需要更多该技术的经验及其完善。