Parthasarathy Anand, Theng Julian, Ti Seng-Ei, Tan Donald T H
Singapore National Eye Centre, Singapore.
J Refract Surg. 2007 Oct;23(8):832-5. doi: 10.3928/1081-597X-20071001-16.
To report two cases of infectious keratitis occurring after laser epithelial keratomileusis (LASEK).
Two patients who underwent LASEK were referred to our center for the management of postoperative infectious keratitis. Infection occurred on postoperative days 2 (case 1) and 5 (case 2). Presenting visual acuity was count fingers in both cases.
Patients were treated aggressively with hourly topical broad-spectrum fortified antibiotics after corneal scrapings were obtained. Culture was positive for Staphylococcus aureus in case 2. Both eyes responded to treatment, resulting in residual corneal scarring with reduced best spectacle-corrected visual acuity of 20/40 in case 1 and uncorrected visual acuity of 20/25 in case 2.
Infectious keratitis can occur after LASEK surgery, and early diagnosis and aggressive therapy are required to aser ereduce visual loss.
报告两例准分子激光上皮下角膜磨镶术（LASEK）后发生的感染性角膜炎病例。
两名接受LASEK手术的患者因术后感染性角膜炎被转诊至我院中心。感染分别发生在术后第2天（病例1）和第5天（病例2）。两例患者就诊时视力均为手动。
获取角膜刮片后，患者每小时接受一次局部强化广谱抗生素积极治疗。病例2的培养结果显示金黄色葡萄球菌阳性。双眼对治疗均有反应，病例1残留角膜瘢痕，最佳矫正视力降至20/40，病例2未矫正视力为20/25。
LASEK手术后可发生感染性角膜炎，需要早期诊断和积极治疗以减少视力丧失。
