Kadowaki Masami, Nagashima Takeshi, Sakata Hiroto, Sakakibara Masahiro, Sangai Takafumi, Nakamura Rikiya, Fujimoto Hiroshi, Arai Manabu, Onai Yasuhide, Nagai Yuichirou, Miyazawa Yukimasa, Miyazaki Masaru
Department of General Surgery, Chiba University Graduate School of Medicine, Chiba, 260-0856, Japan.
Breast Cancer. 2007;14(4):425-8. doi: 10.2325/jbcs.14.425.
Benign epithelial inclusions are uncommonly found in lymph nodes, and ectopic breast tissue in axillary lymph nodes is particularly uncommon. The patient is a 48-year-old woman who had an adenoma of the nipple removed 10 years previously. A swollen lymph node with amorphous calcifications in a clustered distribution on mammogram was found in the left axilla. Fine needle aspiration cytology showed only cystic change. Excisional biopsy was performed and microscopic examination demonstrated that the node contained benign mammary epithelial and glandular inclusions, and no evidence of malignancy. Such cases will be increasingly found due to the widespread use of mammography screening and biopsy of axillary sentinel lymph nodes. Ectopic breast tissue in lymph nodes may be mistaken for malignant lesions. It is most important to identify correctly the epithelial inclusions in lymph nodes to prevent an erroneous diagnosis.
良性上皮性包涵体在淋巴结中罕见,而腋窝淋巴结中的异位乳腺组织尤为少见。患者为一名48岁女性,10年前曾行乳头腺瘤切除术。乳房X线检查发现左腋窝有一个肿大淋巴结,伴有呈簇状分布的无定形钙化。细针穿刺细胞学检查仅显示囊性改变。进行了切除活检,显微镜检查表明该淋巴结含有良性乳腺上皮和腺性包涵体,无恶性证据。由于乳房X线筛查和腋窝前哨淋巴结活检的广泛应用,此类病例将会越来越多地被发现。淋巴结中的异位乳腺组织可能被误诊为恶性病变。正确识别淋巴结中的上皮性包涵体以防止误诊至关重要。