Kolek Martin, Zaloudíková Barbora, Freiberger Tomás, Brát Radim
Department of Cardio Surgery, University Hospital Ostrava, 17 listopadu 1790, Ostrava-Poruba, Czech Republic.
Klin Mikrobiol Infekc Lek. 2007 Oct;13(5):213-6.
A case of blood culture-negative aortic and mitral valve infective endocarditis caused by the bacterium Tropheryma whipplei is reported. A 33-year-old man showed no clinical manifestations of Whipple's disease, with the exception of arthralgia as given in his history. The disease was complicated by recurrent cerebral and left upper limb embolization of vegetations. The causative agent was detected in a valve sample using broad-range polymerase chain reaction. The patient underwent successful surgery (aortic and mitral valve replacement) and his clinical condition during six-month antibiotic therapy was good.
报告了一例由惠普尔嗜组织菌引起的血培养阴性的主动脉瓣和二尖瓣感染性心内膜炎病例。一名33岁男性除了病史中提到的关节痛外，没有惠普尔病的临床表现。该疾病并发赘生物反复脑栓塞和左上肢栓塞。使用广谱聚合酶链反应在瓣膜样本中检测到病原体。患者接受了成功的手术（主动脉瓣和二尖瓣置换术），在为期六个月的抗生素治疗期间临床状况良好。
