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心脏手术后60天术后伤口感染患病率的前瞻性研究。风险因素分析的更新。

A prospective study of prevalence of 60-days postoperative wound infections after cardiac surgery. An updated risk factor analysis.

作者信息

Centofanti P, Savia F, La Torre M, Ceresa F, Sansone F, Veglio V, Fossati L, Guglielmi E, Rinaldi M

机构信息

Department of Cardiac Surgery University of Turin, Turin, Italy.

出版信息

J Cardiovasc Surg (Torino). 2007 Oct;48(5):641-6.

Abstract

AIM

Postoperative wound infections generally cause considerable extra morbidity, mortality and costs. The prevalence of total wound infections after cardiac surgery, including both sternal wound and donor site infections, ranges from 1.3 to 12.8%. The present study was conducted to identify the incidence of wound infections following cardiac surgery, to identify the risk factors and evaluate the efficacy of present modes of management.

METHODS

From September 2004 to May 2005, 493 consecutive patients undergoing cardiac surgery were included in the study and were followed for the prevalence of surgical site infection (SSI) up to 60 days postoperatively. The wound infections were defined according to the Centers for Disease Control and Prevention (CDC) and U.S. National Nosocomial Infections Surveillance (NNIS) system criteria.

RESULTS

The total incidence of SSI was 3.9%. Sternal wound infection (SWI) occurred in 17 patients (3.4%). Superficial wound infection was diagnosed in 10 patients (2%) and deep wound infection in 7 patients (1.4%). Donor site infection (DSI) occurred in 2 patients (0.4%). Early reoperation for bleeding, postoperative dialysis and the use of one internal mammary artery were independently associated with an increased risk of SWI.

CONCLUSION

Preventing SSI in the operating room is the primary goal of the surgical team. Attention should be paid to antibiotic prophylaxis and Methicillin-resistant Staphylococcus aureus (MRSA) nasal carriage treatment. The identification of risk factors will help to further reduce the incidence of wound infection.

摘要

目的

术后伤口感染通常会导致相当多的额外发病率、死亡率和费用。心脏手术后总伤口感染的发生率,包括胸骨伤口和供体部位感染,范围在1.3%至12.8%之间。本研究旨在确定心脏手术后伤口感染的发生率,识别危险因素并评估当前管理模式的疗效。

方法

从2004年9月至2005年5月,493例连续接受心脏手术的患者被纳入研究,并随访至术后60天手术部位感染(SSI)的发生率。伤口感染根据疾病控制与预防中心(CDC)和美国国家医院感染监测(NNIS)系统标准进行定义。

结果

SSI的总发生率为3.9%。17例患者(3.4%)发生胸骨伤口感染(SWI)。10例患者(2%)被诊断为浅表伤口感染,7例患者(1.4%)为深部伤口感染。2例患者(0.4%)发生供体部位感染(DSI)。因出血进行早期再次手术、术后透析以及使用一条胸廓内动脉与SWI风险增加独立相关。

结论

在手术室预防SSI是手术团队的首要目标。应注意抗生素预防和耐甲氧西林金黄色葡萄球菌(MRSA)鼻腔携带的治疗。识别危险因素将有助于进一步降低伤口感染的发生率。

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