Inomata N, Yoshida H, Aoki Y, Tsunoda M, Yamamoto M
Toxicology Section, Central Research Laboratories, Hokuriku Seiyaku Co., Ltd., Fukui.
Tohoku J Exp Med. 1991 Sep;165(1):59-61. doi: 10.1620/tjem.165.59.
Effects of ethyl 4-chloro-2-methylphenoxyacetate (MCPA) and clofibrate on the activities of hepatic lipid metabolizing enzymes in the peroxisomal fraction from rat liver were studied, and these drugs were found to potentiate the peroxisomal enzyme activity. The results imply that MCPA affects lipid metabolism as well as clofibrate.