[The activity of 3',5'-AMP phosphodiesterase and inactivation of insulin during muscular activity].

In trained adult albino rats, more rapid mobilization of carbohydrates and FFA, more economical carbohydrates expenditure during muscular exercise, and more rapid resynthesis of glycogen during recovery period, were observed. This depends on both the changes of 3',5'-AMP-phosphodiesterase activity of muscles, liver, and adipose tissue, and the degree of insulin inactivation by muscle and liver tissues. Both these processes considerably differ in untrained and trained animals.