Chernyshevskaia I A
Zh Evol Biokhim Fiziol. 1991 Jul-Aug;27(4):459-66.
Histochemical studies have been made on the distribution of acetyl- and butyrylcholinesterases (ACHE and BCHE) in various parts of the human and rat brain. Statistical analysis showed that at the 8th week, the highest ACHE activity in the human foetus is observed in the intermediate and plexiform layers of the cerebral cortex. The highest BCHE activity was found in the ependymal layer of various cerebral regions. High BCHE and ACHE activities were noted in the dorsal thalamus and epithalamus. In 10-week human foetuses, total high level of ACHE and BCHE was revealed in various nuclei of the thalamus and subcortical structures of the forebrain (Meynert nucleus, nucleus caudatum). In rats, the highest ACHE activity at the 14th day of prenatal life was found only in subcortical structures of the forebrain. Accumulation of BCHE activity in some of the thalamic nuclei of rats begins at the 10-17th day of postnatal life.
已对人和大鼠大脑各部位的乙酰胆碱酯酶和丁酰胆碱酯酶（ACHE和BCHE）分布进行了组织化学研究。统计分析表明，在第8周时，人类胎儿大脑皮质的中层和丛状层中观察到最高的ACHE活性。在各个脑区的室管膜层中发现了最高的BCHE活性。在背侧丘脑和上丘脑中观察到较高的BCHE和ACHE活性。在10周龄的人类胎儿中，丘脑各核团和前脑的皮质下结构（迈内特核、尾状核）中均显示出ACHE和BCHE的总体高水平。在大鼠中，产前第14天时，仅在前脑的皮质下结构中发现了最高的ACHE活性。大鼠出生后第10 - 17天，一些丘脑核团开始积累BCHE活性。
