Organ procurement in Singapore.

Kidney transplantation, an accepted therapeutic intervention for patients with end stage kidney failure, was pioneered in Singapore on 8 July 1970 by the University Departments of Surgery and Medicine, University of Singapore. Up to 1987, an average of 4.7 cadaveric kidney transplants were performed annually. The introduction of Sandimmune (cyclosporine) in 1985 significantly increased graft survival and consequently created a demand for more cadaveric kidneys for transplantation. The rate of cadaveric kidney transplants escalated to 31.3 kidney transplants annually for the period 1988 to 1990. This increase can be attributed both to the appointment of full time transplant coordinators beginning April 1986 and the implementation of the Human Organ Transplant Act in July 1987. The Human Organ Transplant Act accounted for more than half of all kidneys procured for transplantation (55/94) for the period 1988 to 1990.