Samaranayake Lakshman
Faculty of Dentistry, The University of Hong Kong SAR, China.
Int Dent J. 2007 Oct;57(5):295-9. doi: 10.1111/j.1875-595x.2007.tb00135.x.
The use of saliva as a diagnostic fluid for various human ailments is gaining popularity as it offers distinct advantages over serum. These include the non-invasive nature of saliva collection compared with phlebotomy, simplicity of collection even for individuals with a modest training and the cost-effective applicability for screening large populations. Whole saliva is most frequently used for diagnosis of systemic diseases since it is readily collected and contains serum constituents while gland-specific saliva is useful for investigating pathology of major salivary glands. Broadly, saliva analysis is currently used for the diagnosis of infectious and malignant diseases, hereditary disorders, autoimmune diseases, and endocrine disorders, as well as for the assessment of therapeutic drug levels, particularly in monitoring drug abuse. This review addresses the current status of salivary diagnostics and their future potential.
将唾液用作诊断多种人类疾病的液体正日益受到欢迎，因为与血清相比，它具有明显的优势。这些优势包括与静脉穿刺相比，唾液采集具有非侵入性，即使对于训练有限的个体，采集也很简单，并且在筛查大量人群时具有成本效益。全唾液最常用于系统性疾病的诊断，因为它易于采集且含有血清成分，而特定腺体的唾液则有助于研究主要唾液腺的病理学。广泛而言，唾液分析目前用于诊断感染性和恶性疾病、遗传性疾病、自身免疫性疾病和内分泌疾病，以及评估治疗药物水平，特别是在监测药物滥用方面。本综述阐述了唾液诊断的现状及其未来潜力。
