Stepanova I P
Arkh Anat Gistol Embriol. 1991 May;100(5):21-8.
With the aim to reveal the ionising radiation effect to formation and structure of the optic nerve (ON), 55 white rat intact embryos and fetuses and 77 experimental embryos and fetuses, subjected to x-ray irradiation on the 10th-14th day of development, have been studied. The main regularities in formation of the ON have been stated under normal conditions. Certain disturbances in formation of the ON and in the internal membrane of the optic vesicle (future retina) under effect of x-rays in the dose of 2.24 Gy have been detected during the intrauterine period of development--folds, rosellas of retina, retardation in differentiation of the retina nervous layer, aberration of the ON growth with a subsequent reduction, the ON hypo- and aplasia, retardation in formation of neural sheaths, absence of intraspace between the sheaths.
为揭示电离辐射对视神经（ON）形成和结构的影响，研究了55只完整的白鼠胚胎和胎儿以及77只在发育第10 - 14天接受x射线照射的实验胚胎和胎儿。已阐明正常条件下视神经形成的主要规律。在子宫内发育期间，检测到2.24 Gy剂量的x射线照射对视神经形成以及视泡（未来视网膜）内膜的某些干扰——视网膜褶皱、视网膜玫瑰花结、视网膜神经层分化延迟、视神经生长畸变及随后的萎缩、视神经发育不全和发育不良、神经鞘形成延迟、鞘间间隙缺失。
