• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Molecular mechanisms of erbB2-mediated breast cancer chemoresistance.

作者信息

Tan Ming, Yu Dihua

机构信息

Department of Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

出版信息

Adv Exp Med Biol. 2007;608:119-29. doi: 10.1007/978-0-387-74039-3_9.

DOI:10.1007/978-0-387-74039-3_9
PMID:17993237
Abstract
摘要

相似文献

1
Molecular mechanisms of erbB2-mediated breast cancer chemoresistance.erbB2介导的乳腺癌化疗耐药的分子机制
Adv Exp Med Biol. 2007;608:119-29. doi: 10.1007/978-0-387-74039-3_9.
2
Can trastuzumab be effective against tumors with low HER2/Neu (ErbB2) receptors?曲妥珠单抗对HER2/Neu（ErbB2）受体水平低的肿瘤有效吗？
J Clin Oncol. 2006 Aug 10;24(23):3722-5. doi: 10.1200/JCO.2006.06.5268. Epub 2006 Jul 17.
3
Hypoxia/HIF1α induces lapatinib resistance in ERBB2-positive breast cancer cells via regulation of DUSP2.缺氧/HIF1α通过调控双特异性磷酸酶2（DUSP2）诱导ERBB2阳性乳腺癌细胞对拉帕替尼产生耐药性。
Oncotarget. 2015 Feb 10;6(4):1967-80. doi: 10.18632/oncotarget.2806.
4
Receptor-based predictors of response in breast cancer.基于受体的乳腺癌反应预测指标
Future Oncol. 2009 Apr;5(3):283-6. doi: 10.2217/fon.09.1.
5
Relationship Between HSP70 and ERBB2 Expression in Breast Cancer Cell Lines Regarding Drug Resistance.乳腺癌细胞系中HSP70与ERBB2表达在耐药性方面的关系
Anticancer Res. 2016 Mar;36(3):1243-9.
6
ERBB2 phosphorylation and trastuzumab sensitivity of breast cancer cell lines.乳腺癌细胞系的ERBB2磷酸化与曲妥珠单抗敏感性
Oncogene. 2007 Nov 1;26(50):7163-9. doi: 10.1038/sj.onc.1210528. Epub 2007 May 21.
7
MET and ERBB2 are coexpressed in ERBB2+ breast cancer and contribute to innate resistance.MET 和 ERBB2 在 ERBB2+ 乳腺癌中共同表达，并有助于先天耐药性的产生。
Mol Cancer Res. 2013 Sep;11(9):1112-21. doi: 10.1158/1541-7786.MCR-13-0042. Epub 2013 Jul 3.
8
Overexpression of both p185c-erbB2 and p170mdr-1 renders breast cancer cells highly resistant to taxol.p185c-erbB2和p170mdr-1的过表达使乳腺癌细胞对紫杉醇具有高度抗性。
Oncogene. 1998 Apr 23;16(16):2087-94. doi: 10.1038/sj.onc.1201729.
9
Breast cancer cells respond differently to docetaxel depending on their phenotype and on survivin upregulation.乳腺癌细胞对多西他赛的反应因其表型和生存素上调情况而异。
Tumour Biol. 2016 Feb;37(2):2603-11. doi: 10.1007/s13277-015-4075-x. Epub 2015 Sep 21.
10
Epidermal growth factor receptor coexpression modulates susceptibility to Herceptin in HER2/neu overexpressing breast cancer cells via specific erbB-receptor interaction and activation.表皮生长因子受体共表达通过特定的erbB受体相互作用和激活来调节HER2/neu过表达乳腺癌细胞对赫赛汀的敏感性。
Exp Cell Res. 2005 Apr 1;304(2):604-19. doi: 10.1016/j.yexcr.2004.12.008. Epub 2005 Jan 21.

引用本文的文献

1
Innately Fluorescent Tetravalent Cytotoxic Conjugate TetraF-vcMMAE Engages Aggregation-Dependent Endocytosis of HER2 for Enhanced Intracellular Drug Delivery.具有内在荧光的四价细胞毒性缀合物TetraF-vcMMAE通过HER2的聚集依赖性内吞作用实现增强的细胞内药物递送。
J Med Chem. 2025 Jul 10;68(13):13872-13886. doi: 10.1021/acs.jmedchem.5c00782. Epub 2025 Jun 29.
2
Computational molecular insights into ibrutinib as a potent inhibitor of HER2-L755S mutant in breast cancer: gene expression studies, virtual screening, docking, and molecular dynamics analysis.依鲁替尼作为乳腺癌中HER2-L755S突变体的有效抑制剂的计算分子见解：基因表达研究、虚拟筛选、对接和分子动力学分析。
Front Mol Biosci. 2025 Mar 19;12:1510896. doi: 10.3389/fmolb.2025.1510896. eCollection 2025.
3
Berries as Nature's Therapeutics: Exploring the Potential of Metabolites in Gastric Cancer Treatment Through Computational Insights.浆果作为天然疗法：通过计算洞察探索代谢物在胃癌治疗中的潜力。
Life (Basel). 2025 Mar 5;15(3):406. doi: 10.3390/life15030406.
4
Targeting Cancer With Bifunctional Peptides: Mechanism of Cell Entry and Inciting Cell Death.用双功能肽靶向癌症：细胞进入机制与引发细胞死亡
Cancer Sci. 2025 Jun;116(6):1730-1744. doi: 10.1111/cas.70065. Epub 2025 Mar 26.
5
Cleft Palate Induced by Mycophenolate Mofetil Is Associated with and in Human Palate Cells.霉酚酸酯诱导的腭裂与人腭细胞中的[具体物质1]和[具体物质2]相关。 （注：原文中“and”后面缺失具体内容）
Noncoding RNA. 2025 Feb 6;11(1):12. doi: 10.3390/ncrna11010012.
6
Interstitial Lung Diseases and Non-Small Cell Lung Cancer: Particularities in Pathogenesis and Expression of Driver Mutations.间质性肺疾病和非小细胞肺癌：在发病机制和驱动突变表达方面的特点。
Genes (Basel). 2024 Jul 17;15(7):934. doi: 10.3390/genes15070934.
7
ALLSTAR: Inference of ReliAble CausaL RuLes between Somatic MuTAtions and CanceR Phenotypes.ALLSTAR：体细胞突变与癌症表型之间可靠因果规则的推断
Bioinformatics. 2024 Jul 22;40(7). doi: 10.1093/bioinformatics/btae449.
8
Plasma Metabolome Signatures to Predict Responsiveness to Neoadjuvant Chemotherapy in Breast Cancer.预测乳腺癌新辅助化疗反应性的血浆代谢组学特征
Cancers (Basel). 2024 Jul 6;16(13):2473. doi: 10.3390/cancers16132473.
9
Neuroprotective effects of resveratrol on retinal ganglion cells in glaucoma in rodents: A narrative review.白藜芦醇对啮齿动物青光眼视网膜神经节细胞的神经保护作用：叙事性综述。
Animal Model Exp Med. 2024 Jun;7(3):195-207. doi: 10.1002/ame2.12438. Epub 2024 May 29.
10
Alteration in the expression of the chemotherapy resistance‑related genes in response to chronic and acute hypoxia in pancreatic cancer.胰腺癌中化疗耐药相关基因的表达在慢性和急性缺氧反应中的改变。
Biomed Rep. 2023 Oct 4;19(6):88. doi: 10.3892/br.2023.1670. eCollection 2023 Dec.